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Keywords: Immune synapse
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Cytoskeleton
J Cell Sci (2021) 134 (16): jcs258602.
Published: 27 August 2021
...Keith P. Eidell; Alenka Lovy; Nicholas R. Sylvain; Frank A. Scangarello; Hayley I. Muendlein; Michael J. Ophir; Ken Nguyen; Maria-Cristina Seminario; Stephen C. Bunnell ABSTRACT Integrin engagement within the immune synapse enhances T cell activation, but our understanding of this process...
Includes: Supplementary data
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J Cell Sci (2020) 133 (5): jcs232322.
Published: 4 September 2019
... characteristics, needs careful reconsideration. Actin cytoskeleton Jurkat cells Immune synapse Primary T-cells Wellcome Trust 10.13039/100010269 212343/Z/18/Z Engineering and Physical Sciences Research Council 10.13039/501100000266 EP/S004459/1 Engineering...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (4): jcs219709.
Published: 2 October 2018
.../by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Summary: Immune cell–cell interactions are reconstituted in free-standing vesicles, allowing the spatiotemporal aspects of immune synapse formation...
Includes: Supplementary data
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J Cell Sci (2016) 129 (15): 2881–2886.
Published: 1 August 2016
...Nele M. G. Dieckmann; Gordon L. Frazer; Yukako Asano; Jane C. Stinchcombe; Gillian M. Griffiths ABSTRACT The immune synapse provides an important structure for communication with immune cells. Studies on immune synapses formed by cytotoxic T lymphocytes (CTLs) highlight the dynamic changes...
Includes: Supplementary data
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J Cell Sci (2013) 126 (10): 2176–2186.
Published: 15 May 2013
... cell receptor (TCR) organizes a structured signaling platform at the T cell/APC contact area, known as the immune synapse (IS). Recruitment of PLCγ (phospholipase C γ) to the IS allows rapid hydrolysis of PIP2 (phosphatidylinositol 4,5-bisphosphate), which results in intracellular Ca 2+ release...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1235–1246.
Published: 1 March 2012
... to this work 18 10 2011 © 2012. 2012 Chemotaxis Rho GTPases Immune synapse PDZ Syntenin-1 T cell migration and activation in response to antigen are characterized by morphological changes dictated by the subcellular redistribution of a number of molecules, including chemokine...
Includes: Multimedia, Supplementary data
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Journal Articles
J Cell Sci (2007) 120 (5): 723–730.
Published: 1 March 2007
... of the relevant actin-regulatory proteins, and significant progress has been made in our understanding of how these proteins choreograph molecular movements associated with T-cell activation. Proteins such as WASp, WAVE2, HS1 and cofilin direct the formation of a cortical actin scaffold at the immune synapse...
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