.... Published by The Company of Biologists Ltd 2019 http://www.biologists.com/user-licence-1-1/ Summary: Cytosolic complexes of myosin II, cortexillin I and IQGAPs define the assembly and feedback mechanisms of a mechanoresponsive contractility controller. Myosin II Cortexillin I IQGAP LC...

... is central for understanding cytokinesis. The yeast IQGAP (Iqg1p) belongs to the conserved AMR. The F-BAR-domain-containing protein Hof1p is a member of a complex that stimulates cell wall synthesis. We report here on the stepwise formation of a physical connection between both proteins. The C-terminal IQ...

... and morphogenesis through their effectors. Among the effectors, IQGAP1 plays pivotal roles in the establishment of cytoskeletal architecture and intercellular adhesions in various cells. However, its roles remain to be clarified, especially in neuronal cells. We have identified IQGAP3 as a novel member of the IQGAP...

[email protected] ) 8 12 2006 © The Company of Biologists Limited 2007 2007 Cell motility IQGAP Actin FGF N-WASP Arp2/3 complex IQGAP1 ( Weissbach et al., 1998 ) is an ∼380 kDa homodimeric protein ( Bashour et al., 1997 ) that is widely expressed among vertebrate cell types from...

...James R. Boyne; Hirzun Mohd Yosuf; Pawel Bieganowski; Charles Brenner; Clive Price ABSTRACT MLC1 (myosin light chain) acts as a dosage suppressor of a temperature sensitive mutation in the gene encoding the S. cerevisiae IQGAP protein. Both proteins localize to the bud neck in mitosis although...

...: IQGAP1, L33075; IQGAP2, U51903; DGAP1, L75794; GAPA, D88027; Sar1/Gap1, S37449. In this regard, DGAP1 is similar to the mammalian IQGAPs which are also devoid of RasGAP activity ( Weissbach et al., 1994 ; Brill et al., 1996 ; Hart et al., 1996 ). These proteins lack the catalytic finger arginine...