.... , Robinson , D. N. , Nelson , W. J. and Weis , W. I. ( 2012 ). alpha-catenin and IQGAP regulate myosin localization to control epithelial tube morphogenesis in Dictyostelium . Dev. Cell   23 , 533 - 546 . 10.1016/j.devcel.2012.06.008 Duan , R. , Kim , J. H. , Shilagardi , K...

... is central for understanding cytokinesis. The yeast IQGAP (Iqg1p) belongs to the conserved AMR. The F-BAR-domain-containing protein Hof1p is a member of a complex that stimulates cell wall synthesis. We report here on the stepwise formation of a physical connection between both proteins. The C-terminal IQ...

... and morphogenesis through their effectors. Among the effectors, IQGAP1 plays pivotal roles in the establishment of cytoskeletal architecture and intercellular adhesions in various cells. However, its roles remain to be clarified, especially in neuronal cells. We have identified IQGAP3 as a novel member of the IQGAP...

... of endothelial cells stimulated by VEGF binding to VEGFR2 ( Yamaoka-Tojo et al., 2004 ), and may apply to other growth factor-receptor pairs that await identification. A different member of the IQGAP family, IQGAP2, which is 62% identical in amino acid sequence to IQGAP1 ( Brill et al., 1996 ), may use a related...

...James R. Boyne; Hirzun Mohd Yosuf; Pawel Bieganowski; Charles Brenner; Clive Price ABSTRACT MLC1 (myosin light chain) acts as a dosage suppressor of a temperature sensitive mutation in the gene encoding the S. cerevisiae IQGAP protein. Both proteins localize to the bud neck in mitosis although...

... for correspondence (e-mail: [email protected] ) © 1998 The Company of Biologists Ltd. 1998 Actin cytoskeleton Cell motility Dictyostelium IQGAP Rac The actin cytoskeleton is involved in cell adhesion and motility, mitogenesis, cytokinesis, and establishment of morphology ( Ridley and Hall...