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Thea Shavlakadze, Jinfen Chai, Kirsten Maley, Greg Cozens, Griffin Grounds, Nadine Winn, Nadia Rosenthal, Miranda D. Grounds
J Cell Sci (2010) 123 (6): 960–971.
Published: 15 March 2010
...Thea Shavlakadze; Jinfen Chai; Kirsten Maley; Greg Cozens; Griffin Grounds; Nadine Winn; Nadia Rosenthal; Miranda D. Grounds Here, we characterise new strains of normal and dystrophic ( mdx ) mice that overexpress Class 2 IGF-1 Ea in skeletal myofibres. We show that transgenic mice have increased...
Lisandro Laurino, Xiaoxin X. Wang, Becky A. de la Houssaye, Lucas Sosa, Sebastian Dupraz, Alfredo Cáceres, Karl H. Pfenninger, Santiago Quiroga
J Cell Sci (2005) 118 (16): 3653–3662.
Published: 15 August 2005
... at the nerve growth cone. We have demonstrated recently that plasmalemmal expansion is regulated at the growth cone by IGF-1, but not by BDNF, in a manner that is quasi independent of the neuron's perikaryon. To begin elucidating the signaling pathway by which exocytosis of the plasmalemmal precursor...
J Cell Sci (2003) 116 (15): 3227–3238.
Published: 1 August 2003
... growth factor 1 (IGF-1) influence keratinocyte shape differently. Whereas IGF-1 stimulates membrane protrusion and facilitates cell spreading, EGF induces contraction of keratinocytes. The effects of each growth factor on keratinocyte shape are mediated by distinct signal transduction pathways: EGF...
Karl H. Pfenninger, Lisandro Laurino, Diego Peretti, Xiaoxin Wang, Silvana Rosso, Gerardo Morfini, Alfredo Cáceres, Santiago Quiroga
J Cell Sci (2003) 116 (7): 1209–1217.
Published: 1 April 2003
... and cultures stimulated with brain-derived neurotrophic factor (BDNF), PPV clusters persisted in growth cones with a half-life( t 1/2 ) of >14 minutes. Upon challenge with IGF-1,however, fluorescent elements cleared from the growth cones with a t 1/2 of only 6 minutes. Plasmalemmal expansion was measured...