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Keywords: IFT
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Journal Articles
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Cilia and Flagella
J Cell Sci (2021) 134 (12): jcs247163.
Published: 14 June 2021
...Mareike A. Jordan; Gaia Pigino ABSTRACT The intraflagellar transport (IFT) system is a remarkable molecular machine used by cells to assemble and maintain the cilium, a long organelle extending from eukaryotic cells that gives rise to motility, sensing and signaling. IFT plays a critical role...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (8): 1785–1795.
Published: 15 April 2013
...Joost R. Broekhuis; Suzanne Rademakers; Jan Burghoorn; Gert Jansen Summary Primary cilia are microtubule-based organelles that have important sensory functions. For their function, cilia rely on the delivery of specific proteins, both by intracellular trafficking and intraflagellar transport (IFT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (12): 2077–2084.
Published: 15 June 2010
...Jan Burghoorn; Martijn P. J. Dekkers; Suzanne Rademakers; Ton de Jong; Rob Willemsen; Peter Swoboda; Gert Jansen Cilia length and function are dynamically regulated by modulation of intraflagellar transport (IFT). The cilia of C. elegans amphid channel neurons provide an excellent model to study...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1460–1467.
Published: 01 May 2010
...Christopher Boehlke; Mikhail Bashkurov; Andrea Buescher; Theda Krick; Anne-Katharina John; Roland Nitschke; Gerd Walz; E. Wolfgang Kuehn The structure and function of the primary cilium as a sensory organelle depends on a motor-protein-powered intraflagellar transport system (IFT); defective IFT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (19): 4088–4100.
Published: 01 October 2006
..., we characterized the novel cilia protein T28F3.6 (IFTA-2, intraflagellar transport associated protein 2), which is homologous to the mammalian Rab-like 5 protein. We found that, unlike the intraflagellar transport (IFT) genes, disruption of ifta-2 does not result in overt cilia assembly abnormalities...
Includes: Multimedia, Supplementary data