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Keywords: Huntington's disease
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Journal Articles
J Cell Sci (2018) 131 (13): jcs215343.
Published: 06 July 2018
...Peter A. Mollica; Martina Zamponi; John A. Reid; Deepak K. Sharma; Alyson E. White; Roy C. Ogle; Robert D. Bruno; Patrick C. Sachs ABSTRACT Huntington's disease (HD) is a rare autosomal dominant neurodegenerative disorder caused by a cytosine-adenine-guanine (CAG) trinucleotide repeat (TNR...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (18): 3262–3271.
Published: 15 September 2009
...Marcel Raspe; Judith Gillis; Hilde Krol; Sabine Krom; Klazien Bosch; Henk van Veen; Eric Reits Several neurodegenerative disorders, including Huntington's disease, are caused by expansion of the polyglutamine (polyQ) tract over 40 glutamines in the disease-related protein. Fragments...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (5): 941–948.
Published: 01 March 2002
...Guylaine Hoffner; Pascal Kahlem; Philippe Djian Huntington's disease results from an expansion of a series of glutamine repeats in the protein huntingtin. We have discovered from immunopurification studies that huntingtin combines specifically with the β subunit of tubulin. This binding explains...