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Keywords: Human adipose stem cells
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Journal Articles

CHIR-99021 regulates mitochondrial remodelling via β-catenin signalling and miRNA expression during endodermal differentiation

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Yuejiao Ma, Minghui Ma, Jie Sun, Weihong Li, Yaqiong Li, Xinyue Guo, Haiyan Zhang
Journal: Journal of Cell Science
J Cell Sci (2019) 132 (15): jcs229948.
https://doi.org/10.1242/jcs.229948
Published: 31 July 2019
... inhibitor of glycogen synthase kinase-3α and -3β, CHIR-99021, initiates human adipose stem cell differentiation into human definitive endodermal progenitor cells (hEPCs), which were directed to differentiate synchronously into hepatocyte-like cells after further treatment with combinations of soluble...
View articletitled, CHIR-99021 regulates mitochondrial remodelling via β-catenin signalling and miRNA expression during endodermal differentiation
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Includes: Supplementary data