... Center, 43 New Scotland Avenue, Albany, NY 12208, USA 21 8 2009 © The Company of Biologists Limited 2009 2009 Nma111p HtrA Serine protease Yeast apoptosis Nuclear-localisation signal Higher organisms make use of programmed cell death (apoptosis) during development...

... to antagonise the inhibitor of apoptosis protein XIAP. Here, we report the identification and characterisation of the S. cerevisiae HtrA-like protein, which we termed Nma111p (for nuclear mediator of apoptosis), as a mediator of yeast apoptosis. Nma111p is a nuclear protein that, under cellular stress...