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Keywords: Histone deacetylaseClose
Adam W. Beharry, Pooja B. Sandesara, Brandon M. Roberts, Leonardo F. Ferreira, Sarah M. Senf, Andrew R. Judge
J Cell Sci (2014) 127 (7): 1441–1453.
Published: 1 April 2014
... aimed to determine how histone deacetylase (HDAC) proteins contribute to activation of FoxO and induction of the muscle atrophy program. Through the use of various pharmacological inhibitors to block HDAC activity, we demonstrate that class I HDACs are key regulators of FoxO and the muscle-atrophy...
Katalin Fejes Tóth, Tobias A. Knoch, Malte Wachsmuth, Monika Frank-Stöhr, Michael Stöhr, Christian P. Bacher, Gabriele Müller, Karsten Rippe
J Cell Sci (2004) 117 (18): 4277–4287.
Published: 15 August 2004
... and induced apoptosis. The concentration dependence of both processes was studied. * Author for correspondence (e-mail: firstname.lastname@example.org ) 26 4 2004 © The Company of Biologists Limited 2004 2004 TSA Histone deacetylase Image correlation spectroscopy Fractal...
J Cell Sci (2004) 117 (14): 3021–3029.
Published: 15 June 2004
... in C2C12 myogenic cells, PHB2 inhibits myogenin induction and phenotypic muscle differentiation. PHB2 was found to specifically recruit histone deacetylase 1, which is probably responsible for its repressive activity. Co-expression of Akt can partially reduce PHB2 binding to MyoD and relieve the repressive...