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Keywords: High-content analysis
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Journal Articles
J Cell Sci (2022) 135 (2): jcs259104.
Published: 26 January 2022
... and cell behaviour. We developed a novel image-based endothelial cell profiling tool and quantified heterogeneity in NOTCH signalling in monolayers. Endothelial cells High-content analysis Machine learning NOTCH Heterogeneity King's College London Department of Health http...
Includes: Supplementary data
Journal Articles
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Imaging
J Cell Sci (2018) 131 (1): jcs210419.
Published: 8 January 2018
... in a high-content analysis. The assay relies on a genetically encoded tripartite split-GFP (triSFP) system that we integrated in an optimized cellular model to monitor modulation of RhoA and RhoB GTPases. Our results indicate the robust response of the reporter, allowing the interrogation of inhibition...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (24): 4310–4320.
Published: 15 December 2010
...-conflicting signals is essential during dynamic changes in localization. ERK MAPK Protein kinase C Epidermal growth factor Docking domain Nuclear localization High-content analysis © 2010. 2010 3 9 2010 * Author for correspondence ( craig.mcardle@bristol.ac.uk...
Includes: Supplementary data