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J Cell Sci (2010) 123 (3): 351–359.
Published: 01 February 2010
..., there is no difference in the amino acid sequence of the protein. The N-terminus of GS, which constitutes a ‘weak’ mitochondrial targeting signal (MTS), is sufficient to direct a chimeric protein to the mitochondria in hepatocytes and to the cytoplasm in astrocytes. Considering that a weak MTS is dependent on a highly...
Includes: Supplementary data
Germain Margall-Ducos, Séverine Celton-Morizur, Dominique Couton, Olivier Brégerie, Chantal Desdouets
J Cell Sci (2007) 120 (20): 3633–3639.
Published: 15 October 2007
... or pathological cell division programs leading to tetraploid progenies. In this study we decipher a new mechanism of incomplete cytokinesis taking place in hepatocytes during post-natal liver growth. This process is initiated in vivo after weaning and is associated with an absence of anaphase cell elongation...
Includes: Multimedia, Supplementary data
Josef Gotzmann, Heidemarie Huber, Christiane Thallinger, Markus Wolschek, Burkhard Jansen, Rolf Schulte-Hermann, Hartmut Beug, Wolfgang Mikulits
J Cell Sci (2002) 115 (6): 1189–1202.
Published: 15 March 2002
.... To address this question, we employed immortalized murine hepatocytes, which display a high degree of differentiation and, expectedly, arrest in the G1 phase under exposure to TGF-β1. These hepatocytes maintain epithelial polarization upon expression of oncogenic Ha-Ras. However, Ras-transformed hepatocytes...