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Keywords: Heparan-sulfate proteoglycan (HSPG)
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Journal Articles
Robin N. Prince, Eric R. Schreiter, Peng Zou, H. Steven Wiley, Alice Y. Ting, Richard T. Lee, Douglas A. Lauffenburger
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (13): 2308–2318.
Published: 1 July 2010
..., with these alternatives being governed by the degree of proteolytic release of the ligand. Although the spatial range of diffusion of released HB-EGF is restricted by binding heparan-sulfate proteoglycans (HSPGs) in the extracellular matrix and/or cellular glycocalyx, ascertaining mechanisms governing non-released HB-EGF...
Includes: Supplementary data