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Keywords: Hematopoietic stem cells
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Journal Articles
In collection:
Stem Cells
J Cell Sci (2021) 134 (6): jcs250720.
Published: 11 March 2021
... different regions of human bone marrow revealed them to be functionally distinct hematopoietic stem cell niches. Bone marrow Niche Mesenchymal stem cells Hematopoietic stem cells Metabolomics Transcriptomics Hematopoiesis is a production process of all mature blood cell types that arise...
Includes: Supplementary data
Journal Articles
In collection:
Stem Cells
J Cell Sci (2015) 128 (21): 3849–3860.
Published: 1 November 2015
... of hematopoietic stem cells (HSCs). Several metabolic regulators have been implicated in the maintenance of HSC redox homeostasis; however, the mechanisms that are regulated by ROS and RNS, as well as their downstream signaling are still elusive. This is partially owing to a lack of suitable methods that allow...
Journal Articles
J Cell Sci (2007) 120 (9): 1572–1583.
Published: 1 May 2007
...Xiaoling Zhang; Daniel P. Sejas; Yuhui Qiu; David A. Williams; Qishen Pang The proinflammatory cytokine tumor necrosis factor α (TNFα) inhibits hematopoietic stem cell (HSC) expansion, interferes with HSC self-renewal and compromises the ability of HSC to reconstitute hematopoiesis. We have...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (10): 1985–1991.
Published: 15 May 2006
.... Therefore, there has been an assumption that tissue-specific stem cells might serve as efficient donors for nuclear transfer because of the undifferentiated state of their genome. Here, we show that this is not the case with adult hematopoietic stem cells (HSCs). Although we have demonstrated for the first...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (19): 4343–4352.
Published: 1 October 2005
... of Biologists Limited 2005 2005 Hematopoietic stem cells Bone marrow Skeletal muscle Migration Mammals suffering from radiation-induced anemia or neutropenia can be rescued by intravenous (i.v.) transplantation of healthy bone-marrow (BM)-derived cells ( Ford et al., 1956 ). This observation...