... ). Fast and accurate short read alignment with Burrows-Wheeler Transform . Bioinformatics 25 , 1754 - 1760 . 10.1093/bioinformatics/btp324 Lindquist , S. ( 1986 ). The Heat-Shock response . Annu. Rev. Biochem. 55 , 115 - 191 . 10.1146/annurev.bi.55.070186.005443 Liu...

..., Parkinson's disease and Huntington's disease. Under conditions of cellular stress, activation of the heat shock response (HSR) results in an increase in the levels of molecular chaperones and is a first line of cellular defence against inclusion formation. It remains to be established whether...

...Anshika Goenka; Sonali Sengupta; Rajesh Pandey; Rashmi Parihar; Girish Chandra Mohanta; Mitali Mukerji; Subramaniam Ganesh ABSTRACT The heat shock response is a conserved defense mechanism that protects cells from physiological stress, including thermal stress. Besides the activation of heat-shock...

... (PKC) activator, 12-O-tetradecanoylphorbol 13-acetate (TPA), markedly enhances the heat-induced stress response, and in the present study we elucidate the mechanism by which PKC activation affects the heat shock response in human cells. Our results show that several conventional and novel PKC...