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Keywords: HP1
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Journal Articles
J Cell Sci (2021) 134 (3): jcs257717.
Published: 1 February 2021
... compensatory mechanisms developed by the PA28γ-KO cell line to preserve cellular homeostasis and viability. Interestingly, as already observed in Fig. 1 , these results confirm that even in the presence of HP1 proteins the lack of PA28γ results in a strong decompaction of chromatin. This analysis also...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (15): jcs243303.
Published: 11 August 2020
.... Here, we show that the CENP-B acidic domain recruits histone chaperones and many chromatin modifiers, including the H3K36 methylase ASH1L, as well as the heterochromatin components Suv39h1 and HP1 (HP1α, β and γ, also known as CBX5, CBX1 and CBX3, respectively). ASH1L facilitates the formation of open...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (7): 937–946.
Published: 1 April 2009
... relocalise to novel nucleoplasmic foci that we have termed KRAB- and KAP1-associated (KAKA) foci. HP1s can also concentrate in these foci and there is a close spatial relationship between KAKA nuclear foci and PML nuclear bodies. Finally, we reveal differential requirements for the recruitment of KAP1...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2007) 120 (19): 3415–3424.
Published: 1 October 2007
...George K. Dialynas; Stefan Terjung; Jeremy P. Brown; Rebecca L. Aucott; Bettina Baron-Luhr; Prim B. Singh; Spyros D. Georgatos We have compared the distribution of endogenous heterochromatin protein 1 (HP1) proteins (α, β and γ) in different epithelial lines, pluripotent stem cells and embryonic...
Journal Articles
J Cell Sci (2007) 120 (19): 3425–3435.
Published: 1 October 2007
... of differentiated cells and are universally downregulated during erythropoiesis. Variant-specific patterns are observed in almost all human and mouse tissues examined. Yet, the most instructive example of HP1 plasticity is observed in the lymph nodes, where HP1α and HP1β exhibit regional patterns that are exactly...
Includes: Supplementary data
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J Cell Sci (2004) 117 (22): 5221–5231.
Published: 15 October 2004
... domain at the N-terminus of Orc1p. The same N-terminal region mediates the in vitro interaction with heterochromatin protein 1 (HP1). Fluorescence resonance energy transfer (FRET) experiments demonstrate the interaction of human Orc1p and HP1 in vivo. Our data suggest a role of HP1 in the recruitment...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (1999) 112 (11): 1671–1683.
Published: 1 June 1999
... and cell differentiation. * Author for correspondence (e-mail: chambon@igbmc.u-strasbg.fr ) 04 03 1999 11 05 1999 © 1999 by Company of Biologists 1999 Transcriptional control Coregulator Perichromatin fibril Heterochromatin Embryonic cell HP1 Nuclear receptors...
Journal Articles