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Keywords: HIF-1
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Journal Articles
J Cell Sci (2017) 130 (2): 466–479.
Published: 15 January 2017
...Ilias Mylonis; Maria Kourti; Martina Samiotaki; George Panayotou; George Simos Hypoxia inducible factor-1 (HIF-1) is the main transcriptional activator of the cellular response to hypoxia and an important target of anticancer therapy. Phosphorylation by ERK1 and/or ERK2 (MAPK3 and MAPK1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (4): 956–964.
Published: 15 February 2012
...-containing NADPH oxidase in U-II-induced angiogenesis and elucidated a possible contribution of hypoxia-inducible factor-1 (HIF-1), the master regulator of hypoxic angiogenesis, in the response to U-II. We found that U-II increases angiogenesis in vitro and in vivo, and these responses were prevented...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (17): 2976–2986.
Published: 1 September 2010
...Alkmini Kalousi; Ilias Mylonis; Anastasia S. Politou; Georgia Chachami; Efrosyni Paraskeva; George Simos Hypoxia-inducible factor 1 (HIF-1), a transcriptional activator that mediates cellular response to hypoxia and a promising target of anticancer therapy, is essential for adaptation to low oxygen...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (16): 3351–3362.
Published: 15 August 2006
...Antoine Hubert; Sébastien Paris; Jean-Pascal Piret; Noëlle Ninane; Martine Raes; Carine Michiels HIF-1 (hypoxia-inducible factor-1) is the main transcription factor involved in the adaptation of cells to hypoxia. In addition to regulation of HIF-1α protein level, HIF-1 activity is also enhanced...
Journal Articles
J Cell Sci (2006) 119 (13): 2667–2678.
Published: 1 July 2006
..., several studies suggested that oxygen-dependent gene expression is of crucial importance in governing the essential steps of neurogenesis such as cell proliferation, survival and differentiation. In this context, we analysed the effect of the HIF-1 (hypoxia inducible factor-1) activation-mimicking agent...
Includes: Supplementary data
Journal Articles