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Keywords: HB-EGF
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Journal Articles
J Cell Sci (2017) 130 (7): 1321–1332.
Published: 1 April 2017
...Ryo Iwamoto; Naoki Mine; Hiroto Mizushima; Eisuke Mekada ABSTRACT Heparin-binding EGF-like growth factor (HB-EGF) plays an indispensable role in suppression of cell proliferation during mouse valvulogenesis. However, ligands of the EGF receptor (EGFR/ErbB1), including HB-EGF, are generally...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (23): 4277–4286.
Published: 1 December 2009
... to external stimuli, compared with cells growing in vivo. Here, we showed that the EGFR (epidermal growth factor receptor) ligand heparin-binding EGF-like growth factor (HB-EGF) strongly stimulated cell growth in nude mice, but not in cells cultured in vitro. We explored the effects of HB-EGF on cell growth...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 815–825.
Published: 1 March 2007
...Jia Yin; Keping Xu; Jing Zhang; Ashok Kumar; Fu-Shin X. Yu We have shown previously that wounding of human corneal epithelial (HCE) cells resulted in epidermal growth factor receptor (EGFR) transactivation through ectodomain shedding of heparin-binding EGF-like growth factor (HB-EGF). However...
Journal Articles
J Cell Sci (2005) 118 (11): 2363–2370.
Published: 1 June 2005
... in epithelialization during cutaneous wound healing. Heparin-binding EGF-like growth factor (HB-EGF), a member of the EGF family, is thought to play an important role in skin wound healing. To investigate the in vivo function of HB-EGF in skin wound healing, we generated keratinocyte-specific HB-EGF-deficient mice...