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Keywords: Golgi complex
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Journal Articles
J Cell Sci (2022) 135 (1): jcs258879.
Published: 13 January 2022
... of the secretory pathway. The Golgi complex plays a vital role in directing matrix output by co-ordinating the post-translational modification and proteolytic processing of matrix components prior to their secretion. These modifications have broad impacts on the secretion and subsequent assembly of matrix...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2020) 133 (2): jcs237016.
Published: 29 January 2020
... and the Golgi complex, traffic through the Golgi complex itself and in post-Golgi processes. A large number of studies have assessed the involvement of microtubules in transport of cargo from the Golgi complex to the cell surface. We focus here on the role of kinesin motor proteins and protein interactions...
Journal Articles
In collection:
Polarity
J Cell Sci (2018) 131 (24): jcs219204.
Published: 17 December 2018
... and GSLs are synthesized at the interface between the ER and Golgi complex and constitute the major sphingolipids at the PM. For its metabolic conversions, Cer can be galactosylated in the ER to produce galactosylceramide (GalCer), extracted from ER membranes by the lipid-transfer protein ceramide transfer...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (14): jcs215335.
Published: 19 July 2018
..., and is required for organelle structure and PI(4)P content. Oxysterol binding proteins Golgi complex Membrane contact sites Phosphatidylinositol 4-phosphate The endoplasmic reticulum (ER) is the major site for synthesis of lipids and cholesterol, which are subsequently distributed to other...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (10): 1691–1699.
Published: 15 May 2017
... family, is an important regulator of Golgi complex structure and function in organisms ranging from yeast to mammals. Together with its effectors, Arl1 has been shown to be involved in several cellular processes, including endosomal trans-Golgi network and secretory trafficking, lipid droplet...
Journal Articles
J Cell Sci (2017) 130 (1): 83–89.
Published: 1 January 2017
... at the Golgi complex in distinct and dynamic structures that coexist with autophagosomes in the brain. These structures are composed of several concentric double-membraned layers that appear to be formed simultaneously by the direct bending and sealing of discrete Golgi stacks. These structures are labelled...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (15): 2805–2815.
Published: 1 August 2015
...Kouhei Takashima; Akina Saitoh; Teruki Funabashi; Shohei Hirose; Chikako Yagi; Shohei Nozaki; Ryuichiro Sato; Hye-Won Shin; Kazuhisa Nakayama ABSTRACT Retrograde trafficking from the Golgi complex to endoplasmic reticulum (ER) through COPI-coated vesicles has been implicated in lipid homeostasis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (13): 2293–2302.
Published: 1 July 2015
... characterized in primary glial and cultured cells using fluorescently labeled PLLP and antibodies against PLLP. PLLP localized to and recycled between the plasma membrane and the Golgi complex. In the Golgi complex, PLLP forms oligomers based on fluorescence resonance energy transfer (FRET) analyses. PLLP...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (13): 2259–2268.
Published: 1 July 2015
... that is adjacent to the contractile ring. Cells without Rga7p moved Bgs4p normally from the poles to the Golgi complex near to the cell center, but Bgs4p then moved slowly from the late Golgi compartments to the cleavage site. The late arrival and lower than normal numbers of Bgs4p result in septal defects late...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (12): 2249–2260.
Published: 15 June 2015
...Romina Ines Cervigni; Raffaella Bonavita; Maria Luisa Barretta; Daniela Spano; Inmaculada Ayala; Nobuhiro Nakamura; Daniela Corda; Antonino Colanzi ABSTRACT In mammalian cells, the Golgi complex is composed of stacks that are connected by membranous tubules. During G2, the Golgi complex...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
J Cell Sci (2015) 128 (11): 2021–2032.
Published: 1 June 2015
... trafficking defects, aberrant signaling and disease. * Author for correspondence ( holthuis@uos.de ) Competing interests The authors declare no competing or financial interests. © 2015. Published by The Company of Biologists Ltd 2015 Golgi complex P-type ATPase Flippase Lipid...
Journal Articles
J Cell Sci (2014) 127 (13): 2825–2839.
Published: 1 July 2014
...Yan Shan Ong; Ton Hoai Thi Tran; Natalia V. Gounko; Wanjin Hong ABSTRACT Searching and evaluating the Human Protein Atlas for transmembrane proteins enabled us to identify an integral membrane protein, TMEM115, that is enriched in the Golgi complex. Biochemical and cell biological analysis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (8): 1896–1909.
Published: 15 April 2012
... in HeLa cells.   J. Cell Biol.   168 , 747 – 759 . 10.1083/jcb.200412003 * Author for correspondence ( esztul@uab.edu ) 17 11 2011 © 2012. Published by The Company of Biologists Ltd 2012 Golgi complex p115 Trafficking Uso-1 Secretion in eukaryotic cells involves...
Journal Articles
J Cell Sci (2011) 124 (18): 3118–3126.
Published: 15 September 2011
...-defined. In particular, it is unclear how the unique in vitro biochemical properties of FMNL1 relate to its regulation of cellular processes. Here, we demonstrate that FMNL1 depletion caused a dramatic increase in cellular F-actin content, which resulted in Golgi complex fragmentation. Moreover, increased...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (9): 1496–1509.
Published: 1 May 2011
... to the Golgi complex. Here, comparative genomics, cell biology and phylogenetics were used to probe the early evolution of retromer and its function. Retromer subunits Vps26, Vps29 and Vps35 are near universal, and, by inference, the complex was an ancient feature of eukaryotic cells. Surprisingly, we found...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (6): 978–987.
Published: 15 March 2011
...Carolina Tängemo; Paolo Ronchi; Julien Colombelli; Uta Haselmann; Jeremy C. Simpson; Claude Antony; Ernst H. K. Stelzer; Rainer Pepperkok; Emmanuel G. Reynaud The Golgi complex has a central role in the secretory pathway of all higher organisms. To explain the synthesis of its unique stacked...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (20): 3478–3489.
Published: 15 October 2010
... contributed equally to this work ‡ Author for correspondence ( fangjen@ntu.edu.tw ) 28 6 2010 © 2010. 2010 Golgi complex ADP-ribosylation factor GTPase Vesicular trafficking GEF Sec7 ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins belong to the ARF family, which...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (13): 2218–2227.
Published: 1 July 2009
..., R., Griffiths, G., Frank, R., Argos, P. and Kreis, T. E. ( 1991 ). Beta-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi complex, shows homology to beta-adaptin. Cell 64 , 649 -665. Gaynor, E. C., Graham, T. R. and Emr, S. D. ( 1998 ). COPI in ER/Golgi...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (11): 1759–1767.
Published: 1 June 2009
.... ‡ Author for correspondence (e-mail: koty@post.tau.ac.il ) * These authors contributed equally to this work 16 2 2009 © The Company of Biologists Limited 2009 2009 ER exit sites Golgi complex Endoplasmic reticulum Live-cell imaging Secretory transport Transmembrane domain...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (14): 2406–2414.
Published: 15 July 2008
.... Under such conditions, the Golgi complex is always located towards the leading edge of the cell, suggesting that it is involved in the directional movement. However, several lines of evidence indicate that this location can vary depending on the cell type, the environment or the developmental processes...
Includes: Multimedia, Supplementary data