1-20 of 153
Keywords: Golgi
Close
Sort by
Journal Articles
Journal Articles
J Cell Sci (2023) 136 (10): jcs260923.
Published: 17 May 2023
... that is conserved in CerS proteins and functions through its non-catalytic activity. Tlc4 was localized at the NE and endoplasmic reticulum, similar to CerS proteins, and also showed unique additional localization at the cis- and medial-Golgi cisternae. Growth and mutation analyses revealed that Golgi localization...
Includes: Supplementary data
Journal Articles
In collection:
Membrane trafficking
J Cell Sci (2023) 136 (6): jcs260471.
Published: 6 March 2023
... no competing or financial interests. © 2023. Published by The Company of Biologists Ltd 2023 Summary: A summary of how tethers play a key role in the recognition of specific cargo containers and in membrane fusion. Golgi Rab GTPase SNARE Endosomes Membrane fusion Membrane traffic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (23): jcs259110.
Published: 6 December 2021
...Charlotte Ford; Anup Parchure; Julia von Blume; Christopher G. Burd ABSTRACT The Golgi functions principally in the biogenesis and trafficking of glycoproteins and lipids. It is compartmentalized into multiple flattened adherent membrane sacs termed cisternae, which each contain a distinct...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Membrane trafficking
J Cell Sci (2021) 134 (17): jcs259075.
Published: 7 September 2021
..., the MIA3 gene encodes two major forms of transport and Golgi organization protein 1 (TANGO1S and TANGO1L), which have previously been implicated in selective trafficking of procollagen. Using genome engineering of human cells, light microscopy, secretion assays, genomics and proteomics, we show...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2021) 134 (4): jcs258356.
Published: 19 February 2021
... that the spindle assembly factor TPX2 regulates astral microtubules. TPX2 in the spindle pole area is activated by GM130 (GOLGA2) on Golgi membranes to promote astral microtubule growth. GM130 relieves TPX2 inhibition by competing for importin α1 (KPNA2) binding. Mitotic phosphorylation of importin α at serine 62...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (10): jcs241141.
Published: 27 May 2020
... the Golgi, with TRAPPIII also activating RAB1 in autophagosomes. Our finding that Aspergillus nidulans TRAPPII can be assembled by addition of a TRAPPII-specific subcomplex onto core TRAPP prompted us to investigate the possibility that TRAPPI and/or TRAPPIII already residing in the Golgi matures...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (21): jcs232389.
Published: 1 November 2019
... have identified Golgi proteins as SIRT2 interactors, indicating that SIRT2 may also play a role in Golgi structure formation. Here, we show that SIRT2 depletion causes Golgi fragmentation and impairs Golgi reassembly at the end of mitosis. SIRT2 interacts with the Golgi reassembly stacking protein...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (20): jcs222992.
Published: 21 October 2019
... complex Clathrin Membrane traffic Endocytosis Golgi Hereditary spastic paraplegia Wellcome Trust 10.13039/100004440 086598 214272 Nearly a third of the proteins encoded by the human genome are predicted to be integral membrane proteins, all of which have to get to the right...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (17): jcs230672.
Published: 6 September 2019
...Bhawik Kumar Jain; Roma Dahara; Dibyendu Bhattacharyya ABSTRACT The adhesive force for cisternal stacking of Golgi needs to be reversible – to be initiated and undone in a continuous cycle to keep up with the cisternal maturation. Microscopic evidence in support of such a reversible nature...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (16): jcs231886.
Published: 22 August 2019
...-translational modifications, H-Ras and N-Ras traffic to the PM from the Golgi via the classical exocytic pathway, but the exact mechanism of K-Ras trafficking to the PM from the ER is not fully characterized. ATP5G1 (also known as ATP5MC1) is one of the three proteins that comprise subunit c of the F 0 complex...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2019) 132 (3): jcs225557.
Published: 1 February 2019
... of the Golgi depends on its association with a septin 1 (SEPT1)-based scaffold, which promotes local microtubule nucleation and positioning of the Golgi. SEPT1 function depends on the Golgi matrix protein GM130 (also known as GOLGA2) and on centrosomal proteins, including CEP170 and components of γ-tubulin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (16): jcs215855.
Published: 17 August 2018
...Vibha Singh; Chaitanya Erady; Nagaraj Balasubramanian ABSTRACT Cell-matrix adhesion regulates membrane trafficking controlling anchorage-dependent signaling. While a dynamic Golgi complex can contribute to this pathway, its regulation by adhesion remains unclear. Here we report that loss...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (10): jcs212522.
Published: 23 May 2018
... show that VLDLR is required for mPR trafficking from the endoplasmic reticulum to the Golgi. Taken together, our data define a novel function for the VLDLR as a trafficking chaperone required for the mPR subcellular localization and, as such, non-genomic progesterone-dependent signaling. This article...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (9): jcs212258.
Published: 4 May 2018
... as the most strongly upregulated gene from a comparative RNAseq analysis of cells in which expression of the Golgi matrix protein giantin had been abolished by gene editing. In contrast to previous work where we showed that depletion of giantin by RNAi results in defects in ciliogenesis and in cilia length...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2018) 131 (5): jcs209890.
Published: 13 March 2018
...Eric C. Arakel; Blanche Schwappach ABSTRACT The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (3): jcs210245.
Published: 5 February 2018
... understood. We probed Golgi recruitment of GBF1, a GEF catalyzing ARF activation required for Golgi homeostasis. We show that the homology downstream of Sec7d-1 (HDS1) regulates Golgi recruitment of GBF1. We document that GBF1 binds phosphoinositides, preferentially PI3P, PI4P and PI(4,5)P 2 , and that lipid...
Includes: Supplementary data
Journal Articles