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1-5 of 5
Keywords: Glypican
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (6): jcs259297.
Published: 17 March 2022
...Yulu Cherry Liu; Bradley M. Wierbowski; Adrian Salic ABSTRACT Glypicans are a family of cell surface heparan sulfate proteoglycans that play critical roles in multiple cell signaling pathways. Glypicans consist of a globular core, an unstructured stalk modified with sulfated glycosaminoglycan...
Includes: Supplementary data
Journal Articles
Corinna Ortmann, Ute Pickhinke, Sebastian Exner, Stefanie Ohlig, Roger Lawrence, Hamodah Jboor, Rita Dreier, Kay Grobe
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (12): 2374–2385.
Published: 15 June 2015
... to the cell membrane. We have previously shown that proteolytic removal of both lipidated peptides, called shedding, releases bioactive Sonic hedgehog (Shh) morphogens from the surface of transfected Bosc23 cells. Using in vivo knockdown together with in vitro cell culture studies, we now show that glypican...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (2): 449–460.
Published: 15 January 2012
...Hiroshi Sakane; Hideki Yamamoto; Shinji Matsumoto; Akira Sato; Akira Kikuchi Glypicans are members of the heparan sulfate proteoglycans (HSPGs) and are involved in various growth factor signaling mechanisms. Although HSPGs affect the β-catenin-dependent and -independent pathways of Wnt signaling...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (1): 123–130.
Published: 1 January 2002
...Hiroshi Nakato; Bethany Fox; Scott B. Selleck division abnormally delayed ( dally ) encodes an integral membrane proteoglycan of the glypican family that affects a number of patterning events during both embryonic and larval development. Earlier studies demonstrated that Dally regulates cellular...
Journal Articles
Laina Karthikeyan, Manuela Flad, Margit Engel, Birgit Meyer-Puttlitz, Richard U. Margolis, Renée K. Margolis
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (11): 3213–3222.
Published: 1 November 1994
... of synthesis of glypican, a glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan. Glypican immunoreactivity is present in the marginal layer (prospective white matter) and in the dorsal root entry zone of E13-16 spinal cord, as well as in the optic nerve and retina at this stage, but does...