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Keywords: Glutamine synthetase
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Journal Articles

Weak mitochondrial targeting sequence determines tissue-specific subcellular localization of glutamine synthetase in liver and brain cells

Gideon D. Matthews, Noa Gur, Werner J. H. Koopman, Ophry Pines, Lily Vardimon
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (3): 351–359.
https://doi.org/10.1242/jcs.060749
Published: 1 February 2010
...Gideon D. Matthews; Noa Gur; Werner J. H. Koopman; Ophry Pines; Lily Vardimon Evolution of the uricotelic system for ammonia detoxification required a mechanism for tissue-specific subcellular localization of glutamine synthetase (GS). In uricotelic vertebrates, GS is mitochondrial in liver cells...
View article titled, Weak mitochondrial targeting sequence determines tissue-specific subcellular localization of <span class="search-highlight">glutamine</span> <span class="search-highlight">synthetase</span> in liver and brain cells
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Includes: Supplementary data
Journal Articles

A maternal requirement for glutamine synthetase I for the mitotic cycles of syncytial Drosophila embryos

Lisa M. Frenz, David M. Glover
Journal: Journal of Cell Science
J Cell Sci (1996) 109 (11): 2649–2660.
https://doi.org/10.1242/jcs.109.11.2649
Published: 1 November 1996
...Lisa M. Frenz; David M. Glover ABSTRACT We describe the maternal effect phenotype of a hypomorphic mutation in the Drosophila gene for glutamine synthetase I (GSI). The extent of development of embryos derived from homozygous mutant females is variable, although most mutant embryos fail to survive...
View article titled, A maternal requirement for <span class="search-highlight">glutamine</span> <span class="search-highlight">synthetase</span> I for the mitotic cycles of syncytial Drosophila embryos
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Journal Articles

Uptake of glutamate, not glutamine synthetase, regulates adaptation of mammalian cells to glutamine-free medium

R. H. McDermott, M. Butler
Journal: Journal of Cell Science
J Cell Sci (1993) 104 (1): 51–58.
https://doi.org/10.1242/jcs.104.1.51
Published: 1 January 1993
... no growth in GMEM + gmate. The glutamine synthetase (GS) activity of both cell lines was elevated (up to ×9) as glutamine was depleted from normal media (GMEM gmine). The high activity of GS was maintained during McCoy cell growth in GMEM + gmate. However, there was no apparent significant difference...
View article titled, Uptake of glutamate, not <span class="search-highlight">glutamine</span> <span class="search-highlight">synthetase</span>, regulates adaptation of mammalian cells to glutamine-free medium
Open the PDF for Uptake of glutamate, not <span class="search-highlight">glutamine</span> <span class="search-highlight">synthetase</span>, regulates adaptation of mammalian cells to glutamine-free medium in another window