...Ankit Ghosh; Aastha Varshney; Sunil Kumar Narwal; Nirdosh; Roshni Gupta; Satish Mishra ABSTRACT Plasmodium sporozoites are the infective forms of the malaria parasite in the mosquito and vertebrate host. Gliding motility allows sporozoites to migrate and invade mosquito salivary glands...

... sporozoites migrate at high speed within the skin to access the bloodstream and infect the liver. This unusual gliding motility is based on retrograde flow of membrane proteins and highly dynamic actin filaments that provide short tracks for a myosin motor. Using laser tweezers and parasite mutants, we...

... as a proxy for gliding that can be used to assay for the flagellar components required for gliding motility. Gliding and microsphere movement are dependent on intraflagellar transport (IFT). Circumstantial evidence suggests that mechanical coupling of the IFT force-transducing machinery to a substrate...

... of essential mosquito-stage genes, revealing complementary functions of stage-specific adhesins. Cis-regulatory element Gliding motility Ookinete Sporozoite Transcription Transmission Human Frontier Science Program 10.13039/100004412 RGY0071/2011 Deutsche...

...Dawn M. Wetzel; Lea Ann Chen; Felix A. Ruiz; Silvia N. J. Moreno; L. David Sibley Apicomplexans such as Toxoplasma gondii actively invade host cells using a unique parasite-dependent mechanism termed gliding motility. Calcium-mediated protein secretion by the parasite has been implicated...

...Lawrence W. Bergman; Karine Kaiser; Hisashi Fujioka; Isabelle Coppens; Thomas M. Daly; Sarah Fox; Kai Matuschewski; Victor Nussenzweig; Stefan H. I. Kappe Apicomplexan host cell invasion and gliding motility depend on the parasite's actomyosin system located beneath the plasma membrane of invasive...