... such as the cell cycle, apoptosis and the stress response, to diseases such as cancer. In Caenorhabditis elegans , there are two 14-3-3 genes, ftt-2 and par-5. ftt-2 is expressed only in somatic lineages, whereas par-5 expression is detected in both soma and germline. During early embryonic development, par-5...

... from three experiments with 5000–10,000 events collected per sample. * Author for correspondence ([email protected]) 6 3 2011 © 2011. 2011 Germline Stem cells Wnt signaling Mouse Spermatogonial stem cells (SSCs) are a rare population in testes...

...Yukiko M. Yamashita; Margaret T. Fuller; D. Leanne Jones Stem cells are cells that, upon division, can produce new stem cells as well as daughter cells that initiate differentiation along a specific lineage. Studies using the Drosophila germline as a model system have demonstrated that signaling...

... and differentiation of the germline stem cells, using several signalling molecules, among them the protein DPP – a Drosophila homologue of the human bone morphogenetic proteins BMP2 and BMP4. Recent work shows that D E-cadherin-mediated adhesion is used for the initial recruitment and posterior anchoring...