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Keywords: Gene expression
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Journal Articles
J Cell Sci (2023) 136 (23): jcs261152.
Published: 15 December 2023
... expression analysis of digital gene expression data . Bioinformatics 26 , 139 - 140 . 10.1093/bioinformatics/btp616 Rønnow , S. R. , Dabbagh , R. Q. , Genovese , F. , Nanthakumar , C. B. , Barrett , V. J. , Good , R. B. , Brockbank , S. , Cruwys , S. , Jessen...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (1): jcs259873.
Published: 3 January 2023
... complex is dismantled is essential for appreciating how physiological gene expression is maintained and also how concurrent processes that occur synchronously on the DNA are coordinated. Although the strategies employed by the different classes of eukaryotic RNAPs are traditionally considered...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (19): jcs260082.
Published: 10 October 2022
...) of cancer cells. FOXQ1 may exacerbate cancer by activating the oncogenic Wnt/β-catenin signalling pathway. However, the role of FOXQ1 in the Wnt pathway remains to be resolved. Here, we report that FOXQ1 is an activator of Wnt-induced transcription and regulator of β-catenin target gene expression. Upon Wnt...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2020) 133 (20): jcs254094.
Published: 30 October 2020
... -null cells. Analyses of primary cultures of skin keratinocytes from a mouse strain expressing K17 with a mutated NLS corroborated these findings. Proteomics screens identified K17-interacting nuclear proteins with known roles in gene expression, chromatin organization and RNA processing. Key histone...
Includes: Supplementary data
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J Cell Sci (2014) 127 (7): 1585–1594.
Published: 1 April 2014
... Extracellular vesicle Exosome Gene expression microRNA Cell stress Liver cancer Hypoxia linc-RoR Hepatocellular cancer (HCC) is the fifth most common cancer in men and the seventh most common cancer in women worldwide ( El-Serag, 2012 ). HCC is a highly treatment-resistant malignancy...
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J Cell Sci (2013) 126 (14): 3031–3042.
Published: 15 July 2013
... transcriptional activity is enhanced in the presence of plakoglobin. Our data suggest that plakoglobin regulates gene expression in conjunction with p53 and that plakoglobin may regulate p53 transcriptional activity, which may account, in part, for the tumor/metastasis suppressor activity of plakoglobin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (10): 2294–2304.
Published: 15 May 2013
... glycoprotein gene expression sites, although many members of this diverse family are also transcribed elsewhere in the genome. ESAG9 genes are among the most highly regulated genes in transmissible stumpy forms, encoding a group of secreted proteins of cryptic function. To understand their developmental...
Includes: Supplementary data
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J Cell Sci (2013) 126 (5): 1189–1198.
Published: 1 March 2013
... to define their phenotype as slow or fast twitch muscle fibers. We have previously shown that voltage-gated L-type calcium channel (Cav1.1) acts as a voltage sensor for activation of inositol (1,4,5)-trisphosphate [Ins(1,4,5) P 3 ]-dependent Ca 2+ signals that regulates gene expression. ATP released...
Includes: Supplementary data
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J Cell Sci (2012) 125 (9): 2198–2211.
Published: 1 May 2012
...Kanako Watanabe; Yuki Akimoto; Katsuyuki Yugi; Shinsuke Uda; Jaehoon Chung; Shinichi Nakamuta; Kozo Kaibuchi; Shinya Kuroda A latent process involving signal transduction and gene expression is needed as a preparation step for cellular function. We previously found that nerve growth factor (NGF...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (24): 4318–4331.
Published: 15 December 2011
...Laura Leitner; Dmitry Shaposhnikov; Alexander Mengel; Arnaud Descot; Sylvia Julien; Reinhard Hoffmann; Guido Posern Monomeric actin regulates gene expression through serum response factor (SRF) by inhibiting its transcriptional coactivator myocardin-related transcription factor (MAL/MRTF). Many...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (18): 3174–3186.
Published: 15 September 2011
... address: S. De Bellis Scientific Institute, 70013 Castellana Grotte, Bari, Italy 1 6 2011 © 2011. 2011 PC12 cells NT2/D1 cells Neural cell differentiation Neurosecretion Gene expression The RE-1-specific silencing transcription factor (REST, also referred to as NRSF...
Includes: Supplementary data