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J Cell Sci (2009) 122 (15): 2769–2781.
Published: 1 August 2009
... ). Currently, the mechanosensing signaling pathways that regulate SMA expression are not defined. Because focal-adhesion complexes are putative mechanosensing organelles, we examined the role of focal adhesion kinase (FAK) and its interaction with gelsolin in the regulation of SMA expression. We subjected...
J Cell Sci (2006) 119 (10): 2156–2167.
Published: 15 May 2006
... gelsolin is >100-fold higher than that of C3 cells. Knock-down of gelsolin reduced glucose-stimulated insulin secretion, whereas gelsolin over-expression potentiated secretion from B1 cells. Gelsolin localised along depolymerised actin fibres after glucose stimulation. Taken together, these data...
J Cell Sci (2002) 115 (3): 499–505.
Published: 1 February 2002
...Julian A. Guttman; Paul Janmey; A. Wayne Vogl The gelsolin-phosphoinositide pathway may be part of the normal mechanism by which Sertoli cells regulate sperm release and turnover of the blood-testis barrier. The intercellular adhesion complexes (ectoplasmic specializations)involved with these two...
J Cell Sci (1991) 1991 (Supplement_14): 91–94.
Published: 1 January 1991
..., that common structural features exist between the F-actin binding sites of severing and cross-linking proteins. Molecular biology of actin binding proteins: evidence for a common structural domain in the F-actin binding sites of gelsolin and a-actinin MICHAEL WAY, BRIAN POPE and ALAN WEEDS MRC Laboratory o f...