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Keywords: GM1
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J Cell Sci (2024) 137 (8): jcs261281.
Published: 26 April 2024
... that Aβ oligomers hinder synaptic plasticity, particularly long-term potentiation (LTP), by disrupting GluA1 (encoded by GRIA1 ) function, although the precise mechanism remains unclear. In this study, we demonstrate that Aβ mediates the accumulation of GM1 ganglioside in lipid raft domains of cultured...
Includes: Supplementary data
Journal Articles
In collection:
Lipid biology
J Cell Sci (2011) 124 (15): 2573–2581.
Published: 1 August 2011
... and in vivo. When the GFP-labeled sperm were treated with compounds for promoting the acrosome reaction, EGFP–GPI was released from the sperm surface crosslinked with characteristic relocation of a lipid raft marker ganglioside GM1. Sperm ejaculated into the uterus strongly expressed EGFP–GPI in the head...
Includes: Supplementary data
Journal Articles
In collection:
Lipid biology
J Cell Sci (2009) 122 (2): 289–299.
Published: 15 January 2009
... of integrin and actin. Monosialoganglioside GM1 in the lipid rafts associates with and activates the NGF receptor TrkA, and enhances neurite outgrowth. However, the role of GM1 in laminin-1-induced neurite outgrowth was still unclear. Here, we describe that laminin-1 binds to GM1 through a carbohydrate moiety...
Includes: Supplementary data
Journal Articles
In collection:
Lipid biology
J Cell Sci (2008) 121 (15): 2519–2528.
Published: 1 August 2008
..., such as the EGFR, in biochemically isolated lipid raft fractions. To investigate the role of EGFR activation in the organization of lipid rafts we have performed FLIM analyses using putative lipid raft markers such as ganglioside GM1 and glycosylphosphatidylinositol (GPI)-anchored GFP (GPI-GFP). The EGFR...
Includes: Supplementary data
Journal Articles
In collection:
Lipid biology
J Cell Sci (2005) 118 (14): 3141–3151.
Published: 15 July 2005
... antigen receptor (TCR) and a protein tyrosine kinase, Lck, have a patchy plasma membrane distribution in Jurkat T cells at reduced temperatures, although they have a continuous distribution at physiological temperature (37°C). GM1 displays a patchy distribution at reduced temperature after Triton X-100...