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Keywords: GDF5
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Journal Articles

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation

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Tanja Mang, Kerstin Kleinschmidt-Doerr, Frank Ploeger, Andreas Schoenemann, Sven Lindemann, Anne Gigout
Journal: Journal of Cell Science
J Cell Sci (2020) 133 (16): jcs246934.
https://doi.org/10.1242/jcs.246934
Published: 21 August 2020
...Tanja Mang; Kerstin Kleinschmidt-Doerr; Frank Ploeger; Andreas Schoenemann; Sven Lindemann; Anne Gigout ABSTRACT BMP2 stimulates bone formation and signals preferably through BMP receptor (BMPR) 1A, whereas GDF5 is a cartilage inducer and signals preferably through BMPR1B. Consequently, BMPR1A...
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Includes: Supplementary data
Journal Articles

Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation

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In collection:
Lipid biology
Martha Triantafilou, Kensuke Miyake, Douglas T. Golenbock, Kathy Triantafilou
Journal: Journal of Cell Science
J Cell Sci (2002) 115 (12): 2603–2611.
https://doi.org/10.1242/jcs.115.12.2603
Published: 15 June 2002
... in lipopolysaccharide (LPS)-cellular activation, such as CD14, heat shock protein(hsp) 70, 90, Chemokine receptor 4 (CXCR4), growth differentiation factor 5(GDF5) and Toll-like receptor 4 (TLR4), are present in microdomains following LPS stimulation. Lipid raft integrity is essential for LPS-cellular activation, since...
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