... from host cell membranes by hijacking cellular factors and signaling pathways similar to those involved in the budding of extracellular vesicles. HIV-1 buds from the host cell plasma membrane mainly via the self-assembly of Gag, a structural protein. Gag is a polyprotein that forms assembly complexes...

... GAG binding (Andrievskaia et al., 2007 ; Warner et al., 2002). Increased octarepeats, as seen in some genetic prion diseases, increases the binding capacity and affinity for GAGs, and both increased repeats and increased GAG binding decrease the ability of the cell to respond to ROS (Yin et al., 2006...