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1-2 of 2
Keywords: G3 domain
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Journal Articles
PG-M/versican binds to P-selectin glycoprotein ligand-1 and mediates leukocyte aggregation
Available to PurchasePeng-Sheng Zheng, Dana Vais, David LaPierre, Yao-Yun Liang, Vivian Lee, Bing L. Yang, Burton B. Yang
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (24): 5887–5895.
Published: 15 November 2004
... that PSGL-1 binds to the C-terminal (G3 domain) of the extracellular proteoglycan PG-M/versican. Cells transfected with PSGL-1 or a shorter form containing the binding site, or cells expressing endogenous PSGL-1 aggregate in the presence of versican or G3 product. The aggregation appears to be induced by G3...
Journal Articles
Overexpression of the C-terminal PG-M/versican domain impairs growth of tumor cells by intervening in the interaction between epidermal growth factor receptor and β 1 -integrin
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (11): 2227–2237.
Published: 1 May 2004
...Yaojiong Wu; Liwen Chen; Liu Cao; Wang Sheng; Burton B. Yang Versican is highly expressed in many types of tumors. In a previous study, we found that a G3 mutant [G3ΔEGF; a versican G3 domain lacking two epidermal growth factor (EGF)-like motifs] exerted a dominant-negative effect on versican...
Includes: Supplementary data
