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Keywords: G Protein
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Journal Articles
J Cell Sci (2018) 131 (11): jcs212910.
Published: 05 June 2018
... could be one explanation, but molecular and mechanistic evidence is lacking. In addition to its role in canonical G q pathway activation, here we demonstrate that Opn4 efficiently activates G i heterotrimers and signals through the G protein βγ. Compared with the low levels of G i pathway activation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (6): 1210–1222.
Published: 15 March 2016
...Hisaki Hayashi; Abdullah Al Mamun; Miho Sakima; Motohiko Sato ABSTRACT Activator of G-protein signaling 8 (AGS8, also known as FNDC1) is a receptor-independent accessory protein for the Gβγ subunit, which was isolated from rat heart subjected to repetitive transient ischemia with the substantial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3292–3304.
Published: 01 October 2011
...-associated variants of WDR36 affected its ability to modulate Gαq-mediated signalling by TPβ. We report that WDR36 acts as a new scaffold protein tethering a G-protein-coupled receptor, Gαq and PLCβ in a signalling complex. G-protein-coupled receptors (GPCRs) are the largest family of membrane receptors...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (4): 443–452.
Published: 15 February 2009
... Drosophila GMAP has a role in anterograde transport and Golgi organization in vivo, similar to its mammalian ortholog in tissue culture cells. Eur. J. Cell Biol. 85 , 1155 -1166. Gillingham, A. K. and Munro, S. ( 2007 ). The small G proteins of the Arf family and their regulators. Annu. Rev. Cell...
Journal Articles
J Cell Sci (2006) 119 (12): 2592–2603.
Published: 15 June 2006
... the cation channels TRP and TRP-like (TRPL) are the targets of a prototypical G protein-coupled signaling pathway. We have recently found that the TRPL channel translocates between the rhabdomere and the cell body in a light-dependent manner. This translocation modifies the ion channel composition...
Includes: Supplementary data
Journal Articles
J Cell Sci (2004) 117 (20): 4787–4795.
Published: 15 September 2004
... are not known. Here we investigate the role of two important biochemical pathways - G-protein-dependent and phosphoinositide 3-kinase (PI3K)-dependent signaling - in directing PGC migration in zebrafish. We show that G proteins of the Gi family are essential for directional migration but not for PGC motility...
Includes: Multimedia, Supplementary data