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Keywords: Force spectroscopy
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Journal Articles
J Cell Sci (2011) 124 (11): 1903–1910.
Published: 01 June 2011
... on metastatic colon carcinoma cells. The molecular recognition of CD44v by fibrin mediates firm adhesion at low shear, whereas CD44v–P-selectin binding supports transient rolling interactions at elevated shear stresses and low site densities of P-selectin. We used single-molecule force spectroscopy to provide...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (22): 3965–3976.
Published: 15 November 2007
... loading, at the single-molecule level. Disruption of the actin cytoskeleton resulted in enhanced ALCAM binding avidity, without affecting the tensile strength of the individual bonds. Force spectroscopy revealed that the ALCAM-CD6 bond displayed a significantly higher tensile strength, a smaller reactive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (14): 2960–2967.
Published: 15 July 2006
... cells on the single molecule level. * Author for correspondence (e-mail: peter.hinterdorfer@jku.at ) 3 5 2006 © The Company of Biologists Limited 2006 2006 SGLT1 Na + -D-glucose co-transporter Phlorizin AFM Force spectroscopy The Na + -D-glucose co-transporter...
Journal Articles
J Cell Sci (2004) 117 (12): 2503–2511.
Published: 15 May 2004
...-selectin substrates. The kinetic and mechanical properties of the selectin-ligand bonds responsible for these differences at the single-molecule level are not well understood. Using single-molecule force spectroscopy, we probe in situ the rupture force, unstressed off-rate and reactive compliance of single...
Includes: Supplementary data