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Keywords: Flagellar pocket
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Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2023) 136 (20): jcs261548.
Published: 26 October 2023
... Riemer; Tuguldur Tumurbaatar; Kristina Djinovic-Carugo; Gang Dong; Christian J. Janzen; Brooke Morriswood ABSTRACT All endocytosis and exocytosis in the African trypanosome Trypanosoma brucei occurs at a single subdomain of the plasma membrane. This subdomain, the flagellar pocket, is a small vase-shaped...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (11): 1894–1901.
Published: 1 June 2010
... in the process of cell division. These aberrations include delay in basal body and kinetoplast separation, cleavage furrow progression and flagellar pocket division. In addition to these changes, the intracellular trafficking and actin dynamics are also adversely affected. All these abnormalities are, however...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (23): 5499–5511.
Published: 1 December 2005
...Kevin J. Schwartz; Ronald F. Peck; Ngii N. Tazeh; James D. Bangs Progression of GPI-anchored proteins in bloodstream African trypanosomes correlates with GPI-valence: homodimeric VSG (2 GPI) is a surface protein; heterodimeric transferrin receptor (1 GPI) localizes in the flagellar pocket...
Journal Articles
J Cell Sci (2005) 118 (10): 2105–2118.
Published: 15 May 2005
... the flagellar pocket, which actively communicates by vesicular membrane flow with cisternal/tubulovesicular endosomes. The division of the cell surface into three morphologically distinct sub-domains and the rapid plasma membrane turnover establishes T. brucei as an interesting model for investigations...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (16): 3253–3263.
Published: 15 August 2002
... The Company of Biologists Limited 2002 2002 Trypanosome Lysosome Flagellar pocket Endocytosis LAMP African trypanosomes are parasitic protozoa that cause human (sleeping sickness) and veterinary (Nagana) disease throughout the sub-Saharan continent. Phylogenetically, trypanosomes represent...
Journal Articles
J Cell Sci (2001) 114 (14): 2617–2626.
Published: 15 July 2001
... or markers. Using concanavalin A internalisation and temperature block procedures, TbRAB11 was observed on endomembranes anterior to the flagellar pocket that are juxtaposed to the collecting tubules. TbRAB11 colocalised with the trypanosomal transferrin receptor and internalised antivariant surface...
Journal Articles
J Cell Sci (2000) 113 (22): 4035–4041.
Published: 15 November 2000
... of CPB in vivo . When CPB C25G was expressed in a L. mexicana mutant lacking both CPA and CPB genes, the majority of the pro-enzyme remained unprocessed and accumulated in the flagellar pocket. These data reveal that CPA can directly or indirectly process CPB C25G and suggest that cysteine proteases...
Journal Articles
J Cell Sci (1999) 112 (18): 3061–3070.
Published: 15 September 1999
... Trypanosoma brucei Endosome Golgi Lysosome Flagellar pocket African trypanosomes, namely Trypanosoma brucei spp , are parasitic protozoa that are responsible for a zoonotic disease, sleeping sickness, in sub-Saharan Africa. T. brucei lives in the blood and tissue fluid of its mammalian host...
Journal Articles
Journal Articles
J Cell Sci (1995) 108 (11): 3611–3621.
Published: 1 November 1995
... of bloodstream forms of Trypanosoma brucei rhodesiense . Both markers were rapidly endocytosed from the flagellar pocket. Within 20 minutes at 37°C the markers reached a large, vesicular, perinuclear compartment that stained heavily with the CB1 monoclonal antibody. Neither marker left the flagellar pocket...
Journal Articles
J Cell Sci (1994) 107 (11): 3191–3200.
Published: 1 November 1994
...Marla Jo Brickman; Andrew E. Balber ABSTRACT gp57/42 is a membrane glycoprotein localized in the trans - Golgi, flagellar pocket region of the cell surface, endosomes and lysosomes of bloodstream forms of Trypanosoma brucei rhodesiense . Pulse-chase immunoprecipitation experiments revealed...