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Keywords: Flagellar pocket
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Journal Articles
J Cell Sci (2014) 127 (10): 2351–2364.
Published: 15 May 2014
... have identified and characterized one of the enzymes that is responsible for generating PI(4,5)P 2 . Surprisingly, this phosphoinositide was found to be highly concentrated in the flagellar pocket, the only site of endocytosis and exocytosis in this organism. The enzyme (designated TbPIPKA, annotated...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (11): 1894–1901.
Published: 01 June 2010
... in the process of cell division. These aberrations include delay in basal body and kinetoplast separation, cleavage furrow progression and flagellar pocket division. In addition to these changes, the intracellular trafficking and actin dynamics are also adversely affected. All these abnormalities are, however...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (8): 1081–1090.
Published: 15 April 2009
...Sylvain Lacomble; Sue Vaughan; Catarina Gadelha; Mary K. Morphew; Michael K. Shaw; J. Richard McIntosh; Keith Gull This study uses electron tomography linked to a variety of other EM methods to provide an integrated view of the flagellar pocket and basal body area of the African trypanosome...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (22): 3704–3716.
Published: 15 November 2008
...Sabrina Absalon; Thierry Blisnick; Mélanie Bonhivers; Linda Kohl; Nadège Cayet; Géraldine Toutirais; Johanna Buisson; Derrick Robinson; Philippe Bastin In trypanosomes, the flagellum is rooted in the flagellar pocket, a surface micro-domain that is the sole site for endocytosis and exocytosis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (23): 5499–5511.
Published: 01 December 2005
...Kevin J. Schwartz; Ronald F. Peck; Ngii N. Tazeh; James D. Bangs Progression of GPI-anchored proteins in bloodstream African trypanosomes correlates with GPI-valence: homodimeric VSG (2 GPI) is a surface protein; heterodimeric transferrin receptor (1 GPI) localizes in the flagellar pocket...
Journal Articles
J Cell Sci (2005) 118 (10): 2105–2118.
Published: 15 May 2005
... the flagellar pocket, which actively communicates by vesicular membrane flow with cisternal/tubulovesicular endosomes. The division of the cell surface into three morphologically distinct sub-domains and the rapid plasma membrane turnover establishes T. brucei as an interesting model for investigations...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (16): 3253–3263.
Published: 15 August 2002
.... and Englund, P. T. ( 2000 ). Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promotors. J. Biol. Chem. 275 , 40174 -40179. Webster, P. and Russell, D. G. ( 1993 ). The flagellar pocket of trypanosomatids. Parasitol. Today 9 , 201...
Journal Articles
J Cell Sci (2001) 114 (14): 2617–2626.
Published: 15 July 2001
... or markers. Using concanavalin A internalisation and temperature block procedures, TbRAB11 was observed on endomembranes anterior to the flagellar pocket that are juxtaposed to the collecting tubules. TbRAB11 colocalised with the trypanosomal transferrin receptor and internalised antivariant surface...