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Keywords: Fibrin gelsClose
Journal: Journal of Cell Science
J Cell Sci (2002) 115 (17): 3427–3438.
Published: 1 September 2002
... for tubulogenesis in fibrin gels, instead TIMP-1-insensitive MMPs, such as members of the membrane type-MMPs (MT-MMP) sub-group (MT1-, MT2-, MT3- or MT5-MMP),are required for this process. Further support for a role for MT1-MMP in endothelial tubulogenesis is that recombinant Y36G N-terminal TIMP-2 mutant protein...