... by cell receptor binding, fibronectin conformational changes and macromolecular interactions, as described in this Cell Science at a Glance article. Fibronectin Extracellular matrix Assembly Fibrillogenesis National Institutes of Health http://dx.doi.org/10.13039/100000002 R01...

... fibrillogenesis, blocked the organization of Fn1 nanodomains into periodical arrays. These studies establish a new paradigm of Fn1 fibrillogenesis. This article has an associated First Person interview with the first author of the paper . * Present address: Brainware University, 398 Ramkrishnapur Road...

... regulation of fibrillogenesis. Fibril diameters were significantly increased, with an abnormal, heterogeneous distribution; fibril structure was abnormal, fibril number was decreased and lamellae were disorganized with decreased stroma thickness. The phenotype was more severe in the anterior versus posterior...

... by isoform-selective RNA interference. We show that FN fibrillogenesis is a cell-autonomous process whereby basally directed secretion and assembly of cellular FN are tightly coupled events that play an important role not only in signaling at cell–matrix adhesions but also at cell–cell contacts. Silencing...

.... Studies of the molecular basis of collagen fibrillogenesis have provided insight into the trafficking of procollagen (the precursor of collagen) through the cellular secretory pathway, the conversion of procollagen to collagen by the procollagen metalloproteinases, and the directional deposition...

... © 1995 by Company of Biologists 1995 fibronectin extracellular matrix type I module fibrillogenesis Fibronectin (FN) is a major component of connective tissues and various body fluids. It is a multifunctional, adhesive protein and has been implicated in a wide variety of cellular...

.... † Author for correspondence * This paper is dedicated by J.B.L.B. and D.J.S.H. to John Chapman on the occasion of his retirement 18 03 1993 06 05 1993 © 1993 by Company of Biologists 1993 collagen cornea extracellular matrix fibrillogenesis In most tissues...

... of collagen fibril formation. * Author for correspondence 12 12 1989 10 01 1990 © 1990 by Company of Biologists 1990 collagen fibrillogenesis cornea Collagen molecules are synthesized, secreted into the extracellular space and organized into striated fibrils...