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Keywords: Fascin
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Journal Articles
In collection:
Adhesion , Cytoskeleton
J Cell Sci (2021) 134 (13): jcs258321.
Published: 08 July 2021
... adhesion kinase (FAK; also known as PTK2), the non-nucleated side exhibited a wide flat morphology and was similar in adhesion area to the nucleated side. In cells overexpressing fascin, an actin-bundling protein, the non-nucleated side assumed a spherical shape and was similar in height to the nucleated...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (24): 4601–4614.
Published: 15 December 2015
...Giulia Villari; Asier Jayo; Jennifer Zanet; Briana Fitch; Bryan Serrels; Margaret Frame; Brian M. Stramer; Benjamin T. Goult; Maddy Parsons ABSTRACT Fascin is an actin-binding and bundling protein that is highly upregulated in most epithelial cancers. Fascin promotes cell migration and adhesion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3305–3318.
Published: 01 October 2011
... investigated how the actin-depolymerizing factor cofilin-1 affects the dynamics of fascincrosslinked actin filaments in vitro and in live cells. By multicolor total internal reflection fluorescence microscopy and fluorimetric assays, we found that cofilin-mediated severing is enhanced in fascin-crosslinked...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2002) 115 (11): 2357–2366.
Published: 01 June 2002
... level, TSP-1 supports cell adhesion and migration by the organisation of fascin spike cytoskeletal structures. To define the molecular requirements for assembly of fascin spikes by thrombospondins, we developed a panel of recombinant protein units of TSP-1 and TSP-2; these were designed according...