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Keywords: Fas ligand
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Journal Articles
Sorting of Fas ligand to secretory lysosomes is regulated by mono-ubiquitylation and phosphorylation
Elisabetta Zuccato, Emma J. Blott, Oliver Holt, Sara Sigismund, Michael Shaw, Giovanna Bossi, Gillian M. Griffiths
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (1): 191–199.
Published: 1 January 2007
...Elisabetta Zuccato; Emma J. Blott; Oliver Holt; Sara Sigismund; Michael Shaw; Giovanna Bossi; Gillian M. Griffiths Fas ligand (FasL), a potent mediator of apoptosis expressed by CTL and NK cells, is sorted into the inner vesicles of secretory lysosomes for release via exosome-like vesicles...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (13): 2405–2416.
Published: 1 July 2001
...Emma J. Blott; Giovanna Bossi; Richard Clark; Marketa Zvelebil; Gillian M. Griffiths Fas ligand (FasL) induces apoptosis through its cell surface receptor Fas. T lymphocytes and natural killer cells sort newly synthesised FasL to secretory lysosomes but, in cell types with conventional lysosomes...
