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Keywords: FYVE domain
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Journal Articles
J Cell Sci (2020) 133 (10): jcs244566.
Published: 27 May 2020
...)-phosphate signaling mediated by specific binding to RING FYVE domains . Mol. Cell   2 , 157 - 162 . 10.1016/S1097-2765(00)80125-2 Carvalho , A. F. , Pinto , M. P. , Grou , C. P. , Vitorino , R. , Domingues , P. , Yamao , F. , Sá-Miranda , C. and Azevedo , J. E...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (18): 3071–3083.
Published: 15 September 2010
..., Department of Medicine, Vanderbilt University, Nashville, TN) and cloned into the Kpn1 site of HA-tagged mammalian expression vector pCGN. The MTMR4 C407A construct was generated by site-directed mutagenesis (Quickchange, Stratagene). The MTMR4 PH domain (amino acids 25–125), FYVE domain (amino acids 1109...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (9): 2005–2012.
Published: 01 May 2005
... members, MTMR3 contains a C-terminal FYVE domain. We show that the FYVE domain of MTMR3 is atypical in that it neither confers endosomal localisation nor binds to the lipid PtdIns3 P . Furthermore the FYVE domain is not required for in vitro enzyme activity of MTMR3. In contrast, the PH-GRAM domain...
Journal Articles
J Cell Sci (2005) 118 (3): 575–587.
Published: 01 February 2005
...Li-Fong Seet; Wanjin Hong TOM1 and its related proteins, TOM1-like1 (TOM1-L1) and TOM1-like2 (TOM1-L2), constitute a subfamily of the VHS domain protein family. We have recently shown that endofin, a FYVE domain protein associated with the early endosome, is able to recruit cytosolic TOM1 onto...
Journal Articles
J Cell Sci (2004) 117 (18): 4239–4251.
Published: 15 August 2004
... effects of PtdIns(3) P in these processes, it is important to identify PtdIns(3) P -binding proteins, many of which contain FYVE zinc-finger domains. Here, we describe a novel giant FYVE-domain-containing protein, named autophagy-linked FYVE protein (Alfy). Alfy is ubiquitously expressed, shares sequence...
Journal Articles
J Cell Sci (2002) 115 (24): 4755–4763.
Published: 15 December 2002
...-kinases and FYVE domain proteins, such as EEA1, can be recruited onto early endosomes and act as Rab5 effectors. SARA (Smad anchor for receptor activation), also a FYVE domain protein, was initially isolated as a participant in signal transduction from the transforming growth factorβ receptor...
Journal Articles
J Cell Sci (2001) 114 (22): 3991–4000.
Published: 15 November 2001
... proteins containing one or two FYVE-domains respectively. We show that the FYVE domains in these proteins can bind PtdIns3P in vitro with high specificity over other phosphoinositides. Exogenously expressed FENS-1 localises to early endosomes: this localisation requires an intact FYVE domain...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2001) 114 (12): 2255–2263.
Published: 15 June 2001
..., including an N-terminal VHS domain, a phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding FYVE domain and two coiled-coil domains. Here we have investigated the roles of these domains in the subcellular localisation of Hrs. Hrs was found to colocalise extensively with EEA1, an established marker of early...