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Keywords: FYVE domainClose
In collection:Ubiquitin and Protein Degradation
Christian Renz, Véronique Albanèse, Vera Tröster, Thomas K. Albert, Olivier Santt, Susan C. Jacobs, Anton Khmelinskii, Sébastien Léon, Helle D. Ulrich
J Cell Sci (2020) 133 (10): jcs244566.
Published: 27 May 2020
...)-phosphate signaling mediated by specific binding to RING FYVE domains . Mol. Cell 2 , 157 - 162 . 10.1016/S1097-2765(00)80125-2 Carvalho , A. F. , Pinto , M. P. , Grou , C. P. , Vitorino , R. , Domingues , P. , Yamao , F. , Sá-Miranda , C. and Azevedo , J. E...
Includes: Supplementary data
Monica J. Naughtin, David A. Sheffield, Parvin Rahman, William E. Hughes, Rajendra Gurung, Jennifer L. Stow, Harshal H. Nandurkar, Jennifer M. Dyson, Christina A. Mitchell
J Cell Sci (2010) 123 (18): 3071–3083.
Published: 15 September 2010
..., Department of Medicine, Vanderbilt University, Nashville, TN) and cloned into the Kpn1 site of HA-tagged mammalian expression vector pCGN. The MTMR4 C407A construct was generated by site-directed mutagenesis (Quickchange, Stratagene). The MTMR4 PH domain (amino acids 25–125), FYVE domain (amino acids 1109...
Includes: Supplementary data
J Cell Sci (2005) 118 (9): 2005–2012.
Published: 01 May 2005
... members, MTMR3 contains a C-terminal FYVE domain. We show that the FYVE domain of MTMR3 is atypical in that it neither confers endosomal localisation nor binds to the lipid PtdIns3 P . Furthermore the FYVE domain is not required for in vitro enzyme activity of MTMR3. In contrast, the PH-GRAM domain...
J Cell Sci (2005) 118 (3): 575–587.
Published: 01 February 2005
...Li-Fong Seet; Wanjin Hong TOM1 and its related proteins, TOM1-like1 (TOM1-L1) and TOM1-like2 (TOM1-L2), constitute a subfamily of the VHS domain protein family. We have recently shown that endofin, a FYVE domain protein associated with the early endosome, is able to recruit cytosolic TOM1 onto...
Anne Simonsen, Hanne C. G. Birkeland, David J. Gillooly, Noboru Mizushima, Akiko Kuma, Tamotsu Yoshimori, Thomas Slagsvold, Andreas Brech, Harald Stenmark
J Cell Sci (2004) 117 (18): 4239–4251.
Published: 15 August 2004
... effects of PtdIns(3) P in these processes, it is important to identify PtdIns(3) P -binding proteins, many of which contain FYVE zinc-finger domains. Here, we describe a novel giant FYVE-domain-containing protein, named autophagy-linked FYVE protein (Alfy). Alfy is ubiquitously expressed, shares sequence...
J Cell Sci (2002) 115 (24): 4755–4763.
Published: 15 December 2002
...-kinases and FYVE domain proteins, such as EEA1, can be recruited onto early endosomes and act as Rab5 effectors. SARA (Smad anchor for receptor activation), also a FYVE domain protein, was initially isolated as a participant in signal transduction from the transforming growth factorβ receptor...
S. H. Ridley, N. Ktistakis, K. Davidson, K. E. Anderson, M. Manifava, C. D. Ellson, P. Lipp, M. Bootman, J. Coadwell, A. Nazarian, H. Erdjument-Bromage, P. Tempst, M. A. Cooper, J. W. J. F. Thuring, Z.-Y. Lim, A. B. Holmes, L. R. Stephens, P. T. Hawkins
J Cell Sci (2001) 114 (22): 3991–4000.
Published: 15 November 2001
... proteins containing one or two FYVE-domains respectively. We show that the FYVE domains in these proteins can bind PtdIns3P in vitro with high specificity over other phosphoinositides. Exogenously expressed FENS-1 localises to early endosomes: this localisation requires an intact FYVE domain...
Includes: Multimedia, Supplementary data
Camilla Raiborg, Bjørn Bremnes, Anja Mehlum, David J. Gillooly, Antonello D’Arrigo, Espen Stang, Harald Stenmark
J Cell Sci (2001) 114 (12): 2255–2263.
Published: 15 June 2001
..., including an N-terminal VHS domain, a phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding FYVE domain and two coiled-coil domains. Here we have investigated the roles of these domains in the subcellular localisation of Hrs. Hrs was found to colocalise extensively with EEA1, an established marker of early...