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Keywords: FKBP
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Journal Articles
FKBP52 regulates TRPC3-dependent Ca 2+ signals and the hypertrophic growth of cardiomyocyte cultures
Sandra Bandleon, Patrick P. Strunz, Simone Pickel, Oleksandra Tiapko, Antonella Cellini, Erick Miranda-Laferte, Petra Eder-Negrin
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (20): jcs231506.
Published: 23 October 2019
... of interaction with the functionally intact FKBP52 results in an increased TRPC3 activity and enhanced enlargement of cardiomyocytes. TRPC3 FKBP Calcineurin Calcium Cardiomyocyte The transient receptor potential (TRP; C-classical, TRPC) channels are tetrameric, non-selective ion channels...
Includes: Supplementary data
Journal Articles
In collection:
Cell Biology and Disease
Samantha C. Salvage, Esther M. Gallant, Nicole A. Beard, Shiraz Ahmad, Haseeb Valli, James A. Fraser, Christopher L.-H. Huang, Angela F. Dulhunty
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (10): jcs229039.
Published: 21 May 2019
.... Hyperphosphorylation of RyR2 at S2808 and S2814 is associated with ventricular arrhythmia and FKBP dissociation from RyR2 ( Dobrev and Wehrens, 2014 ). S2808 is hyperphosphorylated in humans and dogs with chronic AF ( Vest et al., 2005 ). Human and rat S2804 and/or S2814 are basally phosphorylated...
Includes: Supplementary data
