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Keywords: Extracellular vesicle
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Journal Articles
J Cell Sci (2022) 135 (7): jcs259628.
Published: 7 April 2022
... have been linked to regulating membrane remodeling, from endosomal recycling to extracellular vesicle formation, through their interactions with lipids and other membrane trafficking regulators, such as ARL1, SNX3 and the kinesin-1 light chain KLC2. Despite these important functions and their likely...
Journal Articles
Journal Articles
J Cell Sci (2019) 132 (6): jcs224212.
Published: 18 March 2019
... and disease. Extracellular vesicles manipulate signaling networks by carrying proteins, lipids, carbohydrates and regulatory nucleic acids. Therefore, they are well positioned to aid in cell-to-cell communication and mediate molecular interactions. This Review briefly discusses exosome and microvesicle...
Journal Articles
J Cell Sci (2018) 131 (15): jcs215210.
Published: 3 August 2018
... biogenesis and autophagy, are linked by the endolysosomal pathway. Exosomes are cargo-laden extracellular vesicles that arise from endosome-derived multivesicular bodies, and autophagy is a lysosomal-dependent degradation and recycling pathway. Recent studies have revealed shared molecular machinery between...
Journal Articles
J Cell Sci (2014) 127 (7): 1585–1594.
Published: 1 April 2014
... expression and increased expression of the linc-RoR target microRNA-145 (miR-145). Linc-RoR was highly expressed in extracellular RNA released by hepatocellular cancer (HCC) cells during hypoxia. Incubation with extracellular vesicle preparations containing extracellular RNA increased linc-RoR, HIF-1α...