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Keywords: Exosome
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Journal Articles
J Cell Sci (2021) 134 (18): jcs253468.
Published: 17 September 2021
... role in the CCM of invasive human colorectal cancer (CRC) epithelium by modulating leading-edge cell dynamics in 2D. The extracellular pool of PLP2, secreted via exosomes, was also found to contribute to the event. During CCM, the protein was found to exist in association with ZO-1 (also known as TJP1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (15): jcs215210.
Published: 3 August 2018
...Jing Xu; Robert Camfield; Sharon M. Gorski ABSTRACT The eukaryotic endomembrane system is a complex series of interconnected membranous organelles that play important roles in responding to stress and maintaining cell homeostasis during health and disease. Two components of this system, exosome...
Journal Articles
Journal Articles
J Cell Sci (2016) 129 (11): 2182–2189.
Published: 1 June 2016
... cells (MSCs), one of the non-endothelial cell types present in the perivascular environment, have been shown to secret exosomes to modulate intercellular communications between MSCs and their target cells. In this study, we initially isolated exosomes secreted by human adipose-derived MSCs (adMSC-Exo...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (6): 1097–1107.
Published: 15 March 2015
...Consuelo Marin-Vicente; Judit Domingo-Prim; Andrea B. Eberle; Neus Visa ABSTRACT The exosome acts on different RNA substrates and plays important roles in RNA metabolism. The fact that short non-coding RNAs are involved in the DNA damage response led us to investigate whether the exosome factor...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (18): 3983–3997.
Published: 15 September 2014
...Cornelia M. Wilson; Thomas Naves; François Vincent; Boris Melloni; François Bonnaud; Fabrice Lalloué; Marie-Odile Jauberteau ABSTRACT The transfer of exosomes containing both genetic and protein materials is necessary for the control of the cancer cell microenvironment to promote tumor angiogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (7): 1585–1594.
Published: 1 April 2014
... Extracellular vesicle Exosome Gene expression microRNA Cell stress Liver cancer Hypoxia linc-RoR Hepatocellular cancer (HCC) is the fifth most common cancer in men and the seventh most common cancer in women worldwide ( El-Serag, 2012 ). HCC is a highly treatment-resistant malignancy...
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (6): 899–906.
Published: 22 February 2004
.... 3 ); moreover, newly made CD2 (a `non-nuclear' cell-surface antigen) can be found in nuclei, and its degradation is closely coupled to transcription ( Fig. 4 ). As inhibiting the proteasome increases nuclear CD2 levels ( Fig. 4C ), and as proteasomal and exosomal subunits lie close to nascent...
Journal Articles
J Cell Sci (2000) 113 (19): 3365–3374.
Published: 1 October 2000
...Kristin Denzer; Monique J. Kleijmeer; Harry F. G. Heijnen; Willem Stoorvogel; Hans J. Geuze ABSTRACT Exosomes are small membrane vesicles that are secreted by a multitude of cell types as a consequence of fusion of multivesicular late endosomes/lysosomes with the plasma membrane. Depending...
Journal Articles
J Cell Sci (1997) 110 (16): 1867–1877.
Published: 15 August 1997
...Michel Vidal; Paul Mangeat; Dick Hoekstra ABSTRACT Endocytosis of the Tf/TfR complex is essentially the only pathway active in maturing reticulocytes, while exosomes, formed by invagination of the endosomal membrane, provide a mechanism to eliminate seemingly obsolescent proteins, including the TfR...