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Keywords: Epithelial polarity
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Journal Articles
J Cell Sci (2021) 134 (18): jcs255927.
Published: 17 September 2021
... lumens in MDCK cysts in 3D cultures. 3D Matrigel culture Epidermal growth factor receptor EGFR Epiregulin EREG Epithelial polarity Epithelial transformation Protein trafficking National Institutes of Health http://dx.doi.org/10.13039/100000002 P50 CA095103 CA248505-01A1 R35...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (6): jcs207779.
Published: 26 March 2018
... polarity remodeling . Curr. Biol.   20 , 1065 - 1074 . 10.1016/j.cub.2010.04.049 Walther , R. F. , Nunes de Almeida , F. , Vlassaks , E. , Burden , J. J. and Pichaud , F. ( 2016 ). Pak4 is required during epithelial polarity remodeling through regulating AJ stability...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (1): 219–231.
Published: 01 January 2017
... polarity depends on the Pax8 transcription factor and is linked to the β1-integrin–laminin pathway through Cdh16. Pax8 Cdh16 Epithelial polarity Thyroid follicle The thyroid follicle is the structural and functional unit of the thyroid gland, and comprises a single layer of follicular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (24): 4538–4549.
Published: 15 December 2015
...Ya-Huei Lin; Heather Currinn; Shirin Meher Pocha; Alice Rothnie; Thomas Wassmer; Elisabeth Knust ABSTRACT Maintenance of epithelial polarity depends on the correct localization and levels of polarity determinants. The evolutionarily conserved transmembrane protein Crumbs is crucial for the size...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (18): 3444–3455.
Published: 15 September 2015
... ). Mechanisms for de novo biogenesis of an apical membrane compartment in groups of simple epithelial cells surrounded by extracellular matrix . J. Cell Sci.   110 , 2781 - 2794 . Rodriguez-Boulan , E. and Macara , I. G. ( 2014 ). Organization and execution of the epithelial polarity programme...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (5): 1011–1022.
Published: 01 March 2015
... ). A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity.   Nature   421 , 379 – 384 . 10.1038/nature01296 Miyoshi   H. , Nakau   M. , Ishikawa   T. O. , Seldin   M. F. , Oshima   M. , Taketo   M. M. ( 2002 ). Gastrointestinal hamartomatous...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2014) 127 (16): 3568–3577.
Published: 15 August 2014
...Anastasia Mashukova; Zhanna Kozhekbaeva; Radia Forteza; Vipin Dulam; Yolanda Figueroa; Robert Warren; Pedro J. Salas ABSTRACT Atypical PKC (ι/λ and ζ; hereafter referred to as aPKC) is a key player in the acquisition of epithelial polarity and participates in other signaling cascades including...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (16): 3585–3592.
Published: 15 August 2013
... Ikenouchi J. and Umeda   M. ( 2010 ). FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex.   Proc. Natl. Acad. Sci. USA.   107 , 748 – 753 . 10.1073/pnas.0908423107 Ikenouchi   J. , Suzuki   M. , Umeda   K. , Ikeda   K. , Taguchi   R...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (20): 3393–3398.
Published: 15 October 2011
...François J.-M. Chartier; Émilie J.-L. Hardy; Patrick Laprise Drosophila Crumbs (Crb) and its mammalian ortholog CRB3 control epithelial polarity through poorly understood molecular mechanisms. Elucidating these mechanisms is crucial, because the physiology of epithelia largely depends...
Journal Articles
J Cell Sci (2011) 124 (19): 3356–3368.
Published: 01 October 2011
... . Development 134 , 789 - 799 . Zegers M. M. , O'Brien L. E. , Yu W. , Datta A. , Mostov K. E. ( 2003 ). Epithelial polarity and tubulogenesis in vitro . Trends Cell Biol. 13 , 169 - 176 . Zheng Z. , Zhu H. , Wan Q. , Liu J. , Xiao Z...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (16): 2861–2871.
Published: 15 August 2011
... core complex. Immobilization of SJ core components coincided with formation of the morphological SJ but occurred after their known role in maintaining epithelial polarity, suggesting that these functions are independent. In striking contrast to the core components, the tumor suppressor protein Discs...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (14): 2491–2503.
Published: 15 July 2009
... Epithelial polarity Protein chaperones Apical kinases The protein kinase C (PKC) family in humans comprises three subclasses: conventional, novel and atypical. They control essential cellular functions ranging from cell proliferation to differentiation, share a highly conserved kinase domain...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (5): 644–654.
Published: 01 March 2008
... for correspondence (e-mail: psalas@med.miami.edu ) 5 12 2007 © The Company of Biologists Limited 2008 2008 ERM proteins Apical domain Brush border Epithelial polarity The sorting mechanisms responsible for the polarization of membrane proteins in epithelial cells, which result...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (17): 3099–3110.
Published: 01 September 2007
...J. Todd Blankenship; Margaret T. Fuller; Jennifer A. Zallen The polarized architecture of epithelial tissues involves a dynamic balance between apical and basolateral membrane domains. Here we show that epithelial polarity in the Drosophila embryo requires the exocyst complex subunit homolog Exo84...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (15): 2594–2608.
Published: 01 August 2007
... in the apoptotic sequence in th 5 embryos. Apoptosis Live imaging Blebbing Epithelial polarity Caspase substrates Drosophila melanogaster provides an excellent model in which to investigate programmed cell death, for its ease of study and because of the high level of conservation of apoptotic...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (18): 4243–4252.
Published: 15 September 2005
... pathway for Cl – exit from absorptive cells. ‡ Author for correspondence (e-mail: fsepulveda@cecs.cl ) * These authors contributed equally to this work 7 6 2005 © The Company of Biologists Limited 2005 2005 ClC-2 Intestinal epithelium Epithelial polarity MDCK cells...
Journal Articles
J Cell Sci (2005) 118 (17): 4049–4057.
Published: 01 September 2005
... not prevent normal junction function or morphology or even epithelial polarity ( Umeda et al., 2004 ). Similarly, downregulation of cingulin, another protein associated with tight junctions, has no effect on tight junction morphology or function but does appear to regulate the expression of several other...
Journal Articles
J Cell Sci (2004) 117 (10): 1899–1909.
Published: 15 April 2004
.... * Author for correspondence (e-mail: thomas@ifn-magdeburg.de ) 1 12 2003 © The Company of Biologists Limited 2004 2004 Epithelial polarity Synapse L27 domain Neuromuscular junction SAP97 Many cell types exhibit an asymmetric subdivison of the plasma membrane...
Journal Articles
J Cell Sci (2002) 115 (23): 4545–4553.
Published: 01 December 2002
... ) 21 8 2002 © The Company of Biologists Limited 2002 2002 Epithelial polarity Membrane traffic SNARE Epithelial cells exhibit characteristic polarized distribution patterns of proteins and lipids on their apical and basolateral plasma-membrane domains( Mostov et al., 2000...
Journal Articles
J Cell Sci (2002) 115 (6): 1189–1202.
Published: 15 March 2002
.... To address this question, we employed immortalized murine hepatocytes, which display a high degree of differentiation and, expectedly, arrest in the G1 phase under exposure to TGF-β1. These hepatocytes maintain epithelial polarization upon expression of oncogenic Ha-Ras. However, Ras-transformed hepatocytes...