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Keywords: Epithelial cells
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Journal Articles
In collection:
Imaging
J Cell Sci (2021) 134 (5): jcs250647.
Published: 23 February 2021
...Amber J. Park; Madison A. Wright; Elyse J. Roach; Cezar M. Khursigara ABSTRACT The age-old saying, seeing is believing, could not be truer when we think about the value of imaging interactions between epithelial cells and bacterial pathogens. Imaging and culturing techniques have vastly improved...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (14): jcs243865.
Published: 27 July 2020
... gradient Epithelial cells ECM Swelling Aquaporin Numerical simulation Dome formation is one of the fundamental processes in morphogenesis. During morphogenesis, 3D shapes are formed due to bending, folding, and elongation of flat epithelial sheets ( Gilmour et al., 2017 ). One example...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (4): jcs221556.
Published: 31 October 2018
...Brian Belardi; Sungmin Son; Michael D. Vahey; Jinzhi Wang; Jianghui Hou; Daniel A. Fletcher ABSTRACT Tight junctions have been hypothesized to act as molecular fences in the plasma membrane of epithelial cells, helping to form differentiated apical and basolateral domains. While this fence function...
Includes: Supplementary data
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2018) 131 (5): jcs208223.
Published: 06 March 2018
.... Moreover, a stiff extracellular matrix dampens the oscillations of the epithelial molecular clock. Here, we extend this analysis to other tissues and cell types, and identify an inverse relationship between circadian clocks in epithelia and fibroblasts. Epithelial cells from mammary gland, lung and skin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (1): 243–259.
Published: 01 January 2017
.... Cell polarity Epithelial Cells Tight junctions Morphogenesis Lumen Formation The ability to form and expand lumens is an essential characteristic of epithelia within tubular organs, such as kidneys and intestines, and is indispensable to their function. Such lumens are lined by a monolayer...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton , Imaging
J Cell Sci (2016) 129 (22): 4278–4288.
Published: 15 November 2016
... cells, microtubules form parallel arrays aligned along the apico–basal axis, and recent work has demonstrated that the members of CAMSAP/Patronin family control apical tethering of microtubule minus ends. Here, we show that in mammalian intestinal epithelial cells, the spectraplakin ACF7 (also known...
Includes: Supplementary data
Journal Articles
In collection:
Cell Migration
J Cell Sci (2016) 129 (21): 4105–4117.
Published: 01 November 2016
.../ Summary: Translation affects adhesion and invasion potential of spreading initiation centers (SICs) producing mesenchymal cells, but not epithelial cells, which are deprived of SICs Spreading initiation centers SICs RNA-binding proteins Focal adhesion Translation regulation Invasion...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (6): 1155–1164.
Published: 15 March 2016
... and smooth septate junctions in developing insect embryos . J. Cell Sci.   56 , 245 - 262 . Lane , N. J. , Dallai , R. , Martinucci , G. and Burighel , P. ( 1994 ). Electron microscopic structure and evolution of epithelial junctions . In Molecular Mechanisms of Epithelial Cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (5): 1051–1063.
Published: 01 March 2015
...Hideki Yamamoto; Chihiro Awada; Shinji Matsumoto; Tomoyuki Kaneiwa; Takayuki Sugimoto; Toshifumi Takao; Akira Kikuchi ABSTRACT Wnt5a regulates planar cell polarity in epithelial cells, but it remains to be determined whether Wnt5a and its receptors are sorted apically or basolaterally, and how...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5127–5137.
Published: 15 December 2014
... declare no competing interests. © 2014. Published by The Company of Biologists Ltd 2014 Epithelial cells Adherens junctions Cytokinesis Epithelia function as mechanical and chemical barriers between the body and the environment. Mono- or multi-layered, these compact tissues...
Journal Articles
J Cell Sci (2014) 127 (6): 1203–1213.
Published: 15 March 2014
... collagen matrices; however, its regulation during tubulogenesis is not understood. Here, we report that degradation of collagen in polarized epithelial cells is post-translationally regulated by changing the localization of MT1-MMP from the apical to the basal surface. MT1-MMP predominantly localizes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (20): 4671–4683.
Published: 15 October 2013
...), that crosslinks MTs through its N-terminal MT-binding region and subsequent coiled-coil motifs. MTCL1 colocalized with the apicobasal MT bundles in epithelial cells, and its knockdown impaired the development of these MT bundles and the epithelial-cell-specific columnar shape. Rescue experiments revealed...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1449–1459.
Published: 01 May 2010
..., and proliferation on epithelial packing . Curr. Biol. 17 , 2095 - 2104 . Fenteany G. , Janmey P. A. , Stossel T. P. ( 2000 ). Signaling pathways and cell mechanics involved in wound closure by epithelial cell sheets . Curr. Biol. 10 , 831 - 838 . Fukatsu K. , Bannai H...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (18): 3374–3384.
Published: 15 September 2009
... of an N-terminal KIND domain, a FERM domain and three PDZ domains. Here we show that FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially colocalizes with the tight-junction marker protein Zonula-occludens-1. Downregulation of FRMPD2 protein in Caco-2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (10): 1595–1606.
Published: 15 May 2009
... ), indicating that they corresponded to vacuolar apical compartments (VACs). PAR aPKC Epithelial cells Polarity Apical domain © The Company of Biologists Limited 2009 2009 10 2 2009 ‡ Present address: Laboratory for Structural Neuropathology, RIKEN Brain Sciences Institute, 2-1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (3): 357–367.
Published: 01 February 2009
... lineages that show differing sensitivities to anoikis. We demonstrate that both fibroblasts and epithelial cells prevent anoikis through FAK activation. We show that FAK activates multiple downstream pathways in order to suppress anoikis. However FAK regulates survival through a more restricted set...
Journal Articles
J Cell Sci (2008) 121 (15): 2481–2492.
Published: 01 August 2008
...Masaru Kishikawa; Atsushi Suzuki; Shigeo Ohno Atypical protein kinase C (aPKC) generally plays crucial roles in the establishment of cell polarity in various biological contexts. In mammalian epithelial cells, aPKC essentially works towards the transition of primordial spot-like adherens junctions...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (13): 2265–2274.
Published: 01 July 2008
... with transmembrane TGFα and decreases its ectodomain shedding to release soluble TGFα. Here we report that CD9 has a role in the maturation of transmembrane TGFα and its stabilization at the cell surface, and in the cell-surface distribution in polarized epithelial cells. Furthermore, coexpression of CD9 and TGFα...
Journal Articles
J Cell Sci (2008) 121 (6): 814–824.
Published: 15 March 2008
.... D. ( 1978 ). Polarized monolayers formed by epithelial cells on a permeable and translucent support. J. Cell Biol. 77 , 853 -880. Cereijido, M., Gonzalez-Mariscal, L., Conreras, R. G., Gallardo, J. M., Garcia-Villegas, R. and Valdes, J. ( 1993 ). The making of a tight junction. J. Cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (4): 458–465.
Published: 15 February 2008
...Delphine Delacour; Annett Koch; Waltraud Ackermann; Isabelle Eude-Le Parco; Hans-Peter Elsässer; Francoise Poirier; Ralf Jacob Epithelial cells are characterised by distinct apical and basolateral membrane domains that are separated by tight junctions. Establishment and maintenance...
Includes: Multimedia, Supplementary data