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Keywords: Endothelin
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Journal Articles
J Cell Sci (2008) 121 (2): 186–195.
Published: 15 January 2008
... to nuclear Ca 2+ signalling in adult cardiomyocytes remains elusive. We tested the hypothesis that endothelin-1 enhances nuclear Ca 2+ concentration transients (CaTs) in rabbit atrial myocytes through Ins(1,4,5) P 3 -induced Ca 2+ release from perinuclear stores. Cytoplasmic and nuclear CaTs were measured...
Journal Articles
J Cell Sci (2006) 119 (16): 3363–3375.
Published: 15 August 2006
... of Gq-coupled agonists. Endothelin-1 augmented the amplitude of pacing-evoked Ca 2+ signals (positive inotropy), and caused an increasing frequency of spontaneous diastolic Ca 2+ -release transients. Both effects of endothelin-1 were blocked by an antagonist of phospholipase C, suggesting that Ins(1,4,5...
Includes: Supplementary data