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1-20 of 212
Keywords: Endoplasmic reticulum
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Journal Articles
In collection:
Membrane Trafficking
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (9): jcs261094.
Published: 9 May 2023
... reticulum protein that binds Sec16p and participates in vesicle formation . J. Cell Biol. 131 , 325 - 338 . 10.1083/jcb.131.2.325 Hammond , A. T. and Glick , B. S. ( 2000 ). Dynamics of transitional endoplasmic reticulum sites in vertebrate cells . Mol. Biol. Cell 11 , 3013...
Includes: Supplementary data
Journal Articles
Stephen M. Coscia, Cameron P. Thompson, Qing Tang, Elana E. Baltrusaitis, Joseph A. Rhodenhiser, Omar A. Quintero-Carmona, E. Michael Ostap, Melike Lakadamyali, Erika L. F. Holzbaur
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (5): jcs260612.
Published: 2 March 2023
... that Myo19 acts as a dynamic actin-binding tether that facilitates mitochondrial fragmentation. Myo19-driven fragmentation was blocked by depletion of either the CAAX splice variant of the endoplasmic reticulum (ER)-anchored formin INF2 or the mitochondrially localized F-actin nucleator Spire1C (a splice...
Includes: Supplementary data
Journal Articles
In collection:
Membrane Trafficking
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (2): jcs260656.
Published: 19 January 2023
...-comments.pdf References Addinsall , A. B. , Wright , C. R. , Andrikopoulos , S. , Van Der Poel , C. and Stupka , N. ( 2018 ). Emerging roles of endoplasmic reticulum-resident selenoproteins in the regulation of cellular stress responses and the implications for metabolic...
Journal Articles
In collection:
Lipid Biology
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (24): jcs260236.
Published: 14 December 2022
... and HIG2 are targeted to LDs, and identify both ATGL-independent and -dependent mechanisms. Structural prediction and studies in cells reveal that ATGL-independent localization of G0S2 to both the endoplasmic reticulum (ER) and LDs is mediated by a hairpin structure consisting of two hydrophobic sequences...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2023) 136 (5): jcs259689.
Published: 16 November 2022
... the factors regulating these different interactions thereby tuning the fascinating endosomal dance. Dynein Dynactin Kinesin Microtubules Endosomes Endoplasmic reticulum Membrane contact sites European Research Council http://dx.doi.org/10.13039/100010663 50438 Nederlandse...
Includes: Supplementary data
Journal Articles
In collection:
Membrane Trafficking
Mary Akinyi Nyonda, Jean-Baptiste Boyer, Lucid Belmudes, Aarti Krishnan, Paco Pino, Yohann Couté, Mathieu Brochet, Thierry Meinnel, Dominique Soldati-Favre, Carmela Giglione
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (15): jcs259811.
Published: 5 August 2022
... in several cell compartments. In mammals, acetyl-CoA transporter 1 (AT1, also known as SLC33A1) facilitates the flux of cytosolic acetyl-CoA into the endoplasmic reticulum (ER), enabling the acetylation of proteins of the secretory pathway, in concert with the activity of dedicated acetyltransferases...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (3): jcs248534.
Published: 7 February 2022
... frontotemporal dementia (ALS/FTD). Many of these changes can be linked to alterations in endoplasmic reticulum (ER)–mitochondria signaling, including dysregulation of Ca 2+ signaling, autophagy, lipid metabolism, ATP production, axonal transport, ER stress responses and synaptic dysfunction. ER–mitochondria...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs259167.
Published: 3 February 2022
... pombe viability under conditions of extreme endoplasmic reticulum stress . J. Cell Biol. 143 , 625 - 635 . 10.1083/jcb.143.3.625 Fernandez , F. S. , Trombetta , S. E. , Hellman , U. and Parodi , A. J. ( 1994 ). Purification to homogeneity of UDP-glucose:glycoprotein...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (1): jcs259254.
Published: 10 January 2022
...Imadeddin Hijazi; Emily Wang; Michelle Orozco; Sarah Pelton; Amy Chang ABSTRACT Endoplasmic reticulum stress (ERS) occurs when cellular demand for protein folding exceeds the capacity of the organelle. Adaptation and cell survival in response to ERS requires a critical contribution by mitochondria...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (21): jcs258856.
Published: 2 November 2021
... by organelles inherited from the mothers. To determine whether this organelle inheritance occurs in a stereotyped manner, we tracked organelles using fluorescence microscopy. We describe a program for organelle inheritance in budding yeast. The cortical endoplasmic reticulum (ER) and peroxisomes are inherited...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs259220.
Published: 2 November 2021
...Pawel Leznicki; Hayden O. Schneider; Jada V. Harvey; Wei Q. Shi; Stephen High ABSTRACT Membrane proteins destined for lipid droplets (LDs), a major intracellular storage site for neutral lipids, are inserted into the endoplasmic reticulum (ER) and then trafficked to LDs where they reside...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (19): jcs259032.
Published: 12 October 2021
... show that both proteins are attached to the cytosolic side of the endoplasmic reticulum membrane. Moreover, an interaction with cytosolic HSP70.1 and HSP90.2 could be shown using bimolecular fluorescence complementation. Knockout of both DJC31 and DJC62 caused severe defects in growth and development...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (18): jcs259156.
Published: 28 September 2021
... pool, indicating a dynamic equilibrium between cytoplasmic and nuclear Dcp1/2. Cytoplasmic Dcp1/2 is linked to Dhh1 via Edc3. Functional P-bodies are present at the endoplasmic reticulum where Dcp2 potentially acts to increase the local concentration of Dhh1 through interaction with Edc3 to drive phase...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs258819.
Published: 10 August 2021
...Stéphanie Cottier; Roger Schneiter ABSTRACT Lipid droplets (LDs) are globular intracellular structures dedicated to the storage of neutral lipids. They are closely associated with the endoplasmic reticulum (ER) and are delineated by a monolayer of phospholipids that is continuous...
Includes: Supplementary data
Journal Articles
In collection:
Lipid Biology
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs256206.
Published: 24 May 2021
...Rasha Khaddaj; Muriel Mari; Stéphanie Cottier; Fulvio Reggiori; Roger Schneiter ABSTRACT Lipid droplets (LDs) are globular subcellular structures that store neutral lipids. LDs are closely associated with the endoplasmic reticulum (ER) and are limited by a phospholipid monolayer harboring...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (5): jcs255026.
Published: 20 April 2021
...Yuan Gao; Juan Xiong; Qing-Zhu Chu; Wei-Ke Ji ABSTRACT Membrane contact sites (MCSs) between the endoplasmic reticulum (ER) and late endosomes/lysosomes (LE/lys) are emerging as critical hubs for diverse cellular events, and changes in their extents are linked to severe neurological diseases. While...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (6): jcs253021.
Published: 26 March 2021
... and Scs22, which are critical for endoplasmic reticulum–plasma membrane contact sites in fission yeast, are also required for microtubule-independent nuclear movement. We also find that in cells in which microtubule-based pushing forces are present, disruption of actin cables leads to increased fluctuations...
Includes: Supplementary data
Journal Articles
In collection:
Cell Biology and Disease
Sarah O'Keefe, Peristera Roboti, Kwabena B. Duah, Guanghui Zong, Hayden Schneider, Wei Q. Shi, Stephen High
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (4): jcs257758.
Published: 19 February 2021
... host biosynthetic machineries and mechanisms. Three major structural proteins, the spike, envelope and membrane proteins, are amongst several SARS-CoV-2 components synthesised at the endoplasmic reticulum (ER) of infected human cells prior to the assembly of new viral particles. Hence, the inhibition...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (22): jcs251983.
Published: 27 November 2020
... in the endoplasmic reticulum (ER). This newly identified quality control pathway employs components of the cytosolic ribosome-associated quality control (RQC) machinery but differs from canonical RQC in that it responds to biogenesis state of the substrate rather than mRNA aberrations. This ER-associated RQC (ER-RQC...
Journal Articles
Fei Wu, Rinse de Boer, Arjen M. Krikken, Arman Akşit, Nicola Bordin, Damien P. Devos, Ida J. van der Klei
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (16): jcs246983.
Published: 17 August 2020
... family proteins localize to the endoplasmic reticulum (ER). Pex24 and Pex32, but not Pex23 and Pex29, predominantly accumulate at peroxisome–ER contacts. Upon deletion of PEX24 or PEX32 – and to a much lesser extent, of PEX23 or PEX29 – peroxisome–ER contacts are lost, concomitant with defects...
Includes: Supplementary data
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