... small GTPase being likely present in a GTP-loaded active form. We analyzed signals from YFP–TTN5 and HA 3 –TTN5 by in situ immunolocalization in Arabidopsis seedlings and through use of a transient expression system. Colocalization with endomembrane markers and pharmacological treatments suggests...

... or retriever complexes. Each comprises a core tri-protein subcomplex, membrane-deformation proteins and interacting partner complexes, together retrieving a variety of known cargo proteins. Trichomonas vaginalis , a sexually transmitted human parasite, uses the endomembrane system for pathogenesis. It has...

... distantly related eukaryotic systems. As much of our understanding of endomembrane system organization is derived from studies in yeast and metazoan systems, organisms without CVCs, the data from which to base comparative studies of CV biogenesis and function is currently lacking. Furthermore, the diverse...

... leukemia (AML). Owing to its constitutive kinase activity FLT3 ITD partially accumulates at endomembranes, a feature shared with other disease-associated, mutated receptor tyrosine kinases. Because Ras proteins also transit through endomembranes we have investigated the possible existence...

...Joel B. Dacks; Mark C. Field The emergence of an endomembrane system was a crucial stage in the prokaryote-to-eukaryote evolutionary transition. Recent genomic and molecular evolutionary analyses have provided insight into how this critical system arrived at its modern configuration. The apparent...

... unknown. Here, we have studied the potential roles of the cytoskeleton and endomembrane system in the localisation of PIN proteins. Immunocytochemistry and image analysis on root cells from Arabidopsis thaliana and maize showed that 10-30% of the intracellular PIN proteins mapped to the Golgi network...