...Beverley Wilson; Chloe Flett; Jakub Gemperle; Craig Lawless; Matthew Hartshorn; Eleanor Hinde; Tess Harrison; Megan Chastney; Sarah Taylor; Jennifer Allen; Jim C. Norman; Thomas Zacharchenko; Patrick T. Caswell ABSTRACT Endocytic recycling controls the return of internalised cargoes to the plasma...

...Hanchong Zhang; Zihang Cheng; Wenbo Li; Jie Hu; Linyue Zhao; Dan Chen; Jinghu Gao; Juan Chen; Yanling Yan; Long Lin; Anbing Shi ABSTRACT The disruption of endosomal actin architecture negatively affects endocytic recycling. However, the underlying homeostatic mechanisms that regulate actin...

.... Endocytic recycling can be rapid, with some molecules returning to the plasma membrane with a half time <5 min. Existing methods to study these trafficking pathways utilize chemical, radioactive or fluorescent labeling of cell surface receptors in pulse-chase experiments, which require tedious washing...

... recycling transport pathway. PAT1 FLCN Rab11A Endocytic recycling mTORC1 Mutations of the tumor suppressor folliculin (FLCN) have been linked with the Birt–Hogg–Dubé (BHD) syndrome that is clinically characterized by benign skin tumors, spontaneous pneumothorax, and kidney cancer ( Birt et...

.... Mitochondria Fission Retromer EHD1 Endocytic recycling VPS35 Rabankyrin-5 Dynamics Mitochondria play an essential role in cellular ATP production via oxidative phosphorylation, but are also crucial for regulating other cellular events including Ca 2+ signaling ( Duchen, 2000 ; Nicholls, 2005...

... of Src from the perinuclear endocytic recycling compartment in response to growth factor stimulation. Our study sheds new light on the mechanism by which Src is transported to the plasma membrane and activated, and provides a new function for MICAL-L1 and EHD1 in the regulation of intracellular non...

... Rab4b effector Endocytic recycling The GTPase Rab4b is phylogenetically conserved from yeast Schizosaccharomyces pombe (Ypt4) to metazoans. The Rab4a orthologous gene is present in Zebrafish and was conserved during evolution through metazoans. Rab4b and Rab4a are encoded by two genes...

...Hotaka Kobayashi; Mitsunori Fukuda Summary Endocytic recycling is a process in which molecules that have been internalized are recycled back to the plasma membrane, and although it is crucial for regulating various cellular events, the molecular nexus underlying this process remains poorly...

... endosomes. The v-SNARE VAMP3 is known to reside in recycling endosomes ( Galli et al., 1994 ; McMahon et al., 1993 ), and has been shown to mediate integrin endocytic recycling ( Tayeb et al., 2005 ; Veale et al., 2010 ). Indeed, dual labeling experiments showed extensive colocalization of accumulated α3...