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Keywords: Embryonic stem cell
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Journal Articles
J Cell Sci (2016) 129 (6): 1165–1178.
Published: 15 March 2016
... is a key regulator of endothelial cell morphology ( Furuyama et al., 2004 ; Hirashima et al., 1999 ). VEGF stimulation induces the elongation of endothelial cells in an in vitro differentiation system of murine embryonic stem cells (ESCs). We have also demonstrated that the endothelial cell elongation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (5): 912–920.
Published: 01 March 2016
.... , Kumar , R. M. , Murray , H. L. , Jenner , R. G. , et al. ( 2005 ). Core transcriptional regulatory circuitry in human embryonic stem cells . Cell   122 , 947 - 956 . 10.1016/j.cell.2005.08.020 Cao , J. , Xiao , Z. , Chen , B. , Gao , Y. , Shi , C. , Wang...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (2): 269–276.
Published: 15 January 2016
...Shoudong Ye; Dongming Zhang; Fei Cheng; Daniel Wilson; Jeffrey Mackay; Kan He; Qian Ban; Feng Lv; Saifei Huang; Dahai Liu; Qi-Long Ying ABSTRACT Activation of leukemia inhibitor factor (LIF)–Stat3 or Wnt/β-catenin signaling promotes mouse embryonic stem cell (mESC) self-renewal. A myriad...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (7): 1500–1510.
Published: 01 April 2014
... for Gli2 activation. To test this hypothesis, we used the Floxin system to create knock-in Gli2 alleles in embryonic stem cells (ESCs) to allow methodical testing of which domains and residues are essential for the ciliary localization of Gli2. The Gli2 zinc fingers, transcriptional activation domain...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (5): 1093–1098.
Published: 01 March 2013
...Chih-I Tai; Qi-Long Ying Summary Activation of signal transducer and activator of transcription 3 (Stat3) by leukemia inhibitory factor (LIF) maintains mouse embryonic stem cell (mESC) self-renewal and also facilitates reprogramming to ground state pluripotency. Exactly how LIF/Stat3 signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (22): 5564–5577.
Published: 15 November 2012
... of NO on murine embryonic stem cells (ESCs) under culture conditions that promote osteogenesis. Expression profiles of NO pathway members and osteoblast-specific markers were analyzed using appropriate assays. We found that NO was supportive of osteogenesis specifically during an early phase of in vitro...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (7): 1673–1682.
Published: 01 April 2012
.... A. , Genchi   G. , Nicotera   P. , et al . ( 2010 ). miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro . Biochem. Biophys. Res. Commun.   394 , 921 - 927 . Du...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (15): 2654–2665.
Published: 01 August 2011
...Jesse L. Cox; Sunil K. Mallanna; Briana D. Ormsbee; Michelle Desler; Matthew S. Wiebe; Angie Rizzino Self-renewal is a complex biological process necessary for maintaining the pluripotency of embryonic stem cells (ESCs). Recent studies have used global proteomic techniques to identify proteins...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (10): 1684–1692.
Published: 15 May 2010
... of BMP-9 on the proliferation of endothelial cells. Vascular-tube formation from ex vivo allantoic explants of mouse embryos was promoted by BMP-9. BMP-9, as well as BMP-4 and BMP-6, also induced the proliferation of in-vitro-cultured mouse embryonic-stem-cell-derived endothelial cells (MESECs...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (20): 3729–3737.
Published: 15 October 2009
...Li Luo; Katherine L. Gassman; Lydia M. Petell; Christian L. Wilson; Joerg Bewersdorf; Lindsay S. Shopland Chromatin adapts a distinct structure and epigenetic state in embryonic stem cells (ESCs), but how chromatin is three-dimensionally organized within the ESC nucleus is poorly understood...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (20): 3317–3324.
Published: 15 October 2008
... important roles during mural differentiation of mouse embryonic stem cell-derived endothelial cells (MESECs). TGFβ2 induced the differentiation of MESECs into mural cells, with a decrease in the expression of the endothelial marker claudin 5, and an increase in expression of the mural markers smooth muscle...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 885–894.
Published: 01 March 2007
...., Anisimov, S. V. and Wobus, A. M. ( 2002 ). Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ. Res. 91 , 189 -201. Buesen, R., Visan, A., Genschow, E., Slawik, B., Spielmann, H. and Seiler, A. ( 2004 ). Trends in improving the embryonic stem cell test (EST): an overview...
Journal Articles
J Cell Sci (2007) 120 (1): 55–65.
Published: 01 January 2007
... award (to H.N. and K.M.), and Leading Project (to H.N.). References Beattie, G. M., Lopez, A. D., Bucay, N., Hinton, A., Firpo, M. T., King, C. C. and Hayek, A. ( 2005 ). Activin a maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells 23 , 489 -495...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (17): 3861–3868.
Published: 01 September 2005
...Anne E. Wiblin; Wei Cui; A. John Clark; Wendy A. Bickmore Nuclear organisation is thought to be important in regulating gene expression. Here we investigate whether human embryonic stem cells (hES) have a particular nuclear organisation, which could be important for maintaining their pluripotent...
Journal Articles
J Cell Sci (2004) 117 (23): 5681–5686.
Published: 01 November 2004
...Takashi Hamazaki; Masahiro Oka; Shinya Yamanaka; Naohiro Terada When embryonic stem cells are allowed to aggregate, the outer layer of the aggregated spheres (referred to as embryoid bodies) differentiates into primitive endoderm. This initial specification of cell lineage facilitates further...