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Keywords: Elk-1
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Journal Articles
J Cell Sci (2009) 122 (18): 3340–3350.
Published: 15 September 2009
...) or a dominant-negative mutant of Elk-1 (a key regulator of Egr-1 biosynthesis) abolished EGF-induced proliferation of astrocytes. Chromatin immunoprecipitation experiments showed that Egr-1, Egr-2 and Egr-3 bound to the gene expressing basic fibroblast growth factor (bFGF) in EGF-stimulated astrocytes. Egr-2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (13): 2781–2790.
Published: 1 July 2002
... or by expression of upstream activators. Under conditions whereby JNK activation is anchorage-independent, we show that localization of JNK to the nucleus and JNK-mediated phosphorylation of c-Jun and Elk-1 is not altered by loss of adhesion. Likewise, the ability of activated p38 to accumulate in the nucleus...