... of the pluripotency of embryonic stem (ES) cells and that the transcriptional activity of Myc is regulated by several post-translational modifications, including ubiquitination. In this study, we showed that tripartite motif containing 6 (TRIM6), one of the TRIM family ubiquitin ligases, was selectively expressed...

... proteins produced in animal or Escherichia coli cells have not been devised. Here, we report a defined culture method using low-molecular-mass compounds that induce differentiation of human embryonic stem (ES) cells and induced pluripotent stem (iPS) cells into retinal progenitors, retinal pigment...

... ) 6 7 2004 In summary, we have demonstrated that targeted deletion of most of the head domain of cingulin in ES cells abolishes cingulin junctional recruitment without preventing TJ formation in epithelial cells of differentiated EBs. We showed that junctional cingulin is not required either...