1-20 of 38
Keywords: EMT
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2023) 136 (17): jcs260934.
Published: 1 September 2023
...Marko Marjanović; Ana-Matea Mikecin Dražić; Marija Mioč; Mladen Paradžik; Filip Kliček; Mislav Novokmet; Gordan Lauc; Marijeta Kralj ABSTRACT Epithelial-to-mesenchymal transition (EMT) gives rise to cells with properties similar to cancer stem cells (CSCs). Targeting the EMT program to selectively...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (21): jcs258418.
Published: 5 November 2021
... by epithelial-to-mesenchymal transition (EMT). Mounting evidence has indicated that long non-coding RNAs (lncRNAs) also contribute to tumor progression. We report the identification of 114 novel lncRNAs that change their expression during TGFβ-induced EMT in murine breast cancer cells (referred to as EMT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (15): jcs228213.
Published: 31 July 2019
... signaling. We found that clusterin potentiated the effects of eHsp90α on activation of the AKT, ERK and NF-κB protein families, epithelial-to-mesenchymal transition (EMT) and migration in breast cancer cells. Furthermore, in vivo investigations demonstrated similar synergistic effects of eHsp90α...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (21): jcs216168.
Published: 29 October 2018
...Varisa Pongrakhananon; Onsurang Wattanathamsan; Masatoshi Takeichi; Paninee Chetprayoon; Pithi Chanvorachote ABSTRACT Epithelial-to-mesenchymal transition (EMT) plays pivotal roles in a variety of biological processes, including cancer invasion. Although EMT involves alterations of cytoskeletal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (14): jcs208314.
Published: 26 July 2018
...Meera Saxena; Sai A. Balaji; Neha Deshpande; Santhalakshmi Ranganathan; Divya Mohan Pillai; Sravanth Kumar Hindupur; Annapoorni Rangarajan ABSTRACT The developmental programme of epithelial-mesenchymal transition (EMT), involving loss of epithelial and acquisition of mesenchymal properties, plays...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (21): 3749–3763.
Published: 1 November 2017
... to MNU inhibited polarisation at the basolateral domain, increased dispersal of the Golgi at the apical domain and induced an epithelial-to-mesenchymal transition (EMT)-like phenotype as well as invasion. This altered Golgi phenotype correlated with impaired intracellular trafficking. Inhibition of DNA...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (6): 1078–1093.
Published: 15 March 2017
...Jing Wang; Kumar Nikhil; Keith Viccaro; Lei Chang; Max Jacobsen; George Sandusky; Kavita Shah ABSTRACT We uncovered a crucial role for the Aurora kinase A (AURKA)–Twist1 axis in promoting epithelial-to-mesenchymal transition (EMT) and chemoresistance in pancreatic cancer. Twist1 is the first EMT...
Includes: Supplementary data
Journal Articles
In collection:
Cell migration
J Cell Sci (2016) 129 (21): 4105–4117.
Published: 1 November 2016
...Jonathan Bergeman; Alexia Caillier; François Houle; Laurence M. Gagné; Marc-Étienne Huot ABSTRACT Epithelial-to-mesenchymal transition (EMT) is a process by which cancer cells gain the ability to leave the primary tumor site and invade surrounding tissues. These metastatic cancer cells can further...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (11): 2047–2056.
Published: 1 June 2015
... interests The authors declare no competing or financial interests. 21 7 2014 14 4 2015 © 2015. Published by The Company of Biologists Ltd 2015 Rac Rho Adherens junctions E-cadherin EMT Cell–cell adhesion is essential for epithelial tissue integrity and function...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (9): 1773–1786.
Published: 1 May 2015
...Rangarajan Padmanabhan; Lisa A. Taneyhill The epithelial‐to‐mesenchymal transition (EMT) is important for the formation of migratory neural crest cells during development and is co‐opted in human diseases such as cancer metastasis. Chick premigratory cranial neural crest cells lose intercellular...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4740–4749.
Published: 1 November 2014
...Omer Keinan; Amir Kedan; Nancy Gavert; Michael Selitrennik; SoHui Kim; Thomas Karn; Sven Becker; Sima Lev ABSTRACT The involvement of epithelial-mesenchymal transition (EMT) in breast cancer metastasis has been demonstrated in many studies. However, the intracellular proteins and signaling pathways...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (10): 2326–2338.
Published: 15 May 2014
...Ewa Grudzien-Nogalska; Brent C. Reed; Robert E. Rhoads ABSTRACT Downregulation of CPEB1, a sequence-specific RNA-binding protein, in a mouse mammary epithelial cell line (CID-9) causes epithelial-to-mesenchymal transition (EMT), based on several criteria. First, CPEB1 knockdown decreases protein...
Journal Articles
J Cell Sci (2014) 127 (9): 2017–2028.
Published: 1 May 2014
... processes requiring cell movement. Specifically, they regulate epithelial-to-mesenchymal transitions (EMT) where an epithelial cell severs intercellular junctions, degrades basement membrane and becomes a migratory, mesenchymal-like cell. Interestingly, Slug expression has been observed in angiogenic...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2013) 126 (17): 3939–3947.
Published: 1 September 2013
...Lina Sun; He Li; Junliang Chen; Yasumasa Iwasaki; Toru Kubota; Mayumi Matsuoka; Aiguo Shen; Qi Chen; Yong Xu Summary Epithelial-mesenchymal transition (EMT) has an essential role in organogenesis and contributes to a host of pathologies, including carcinogenesis. Hypoxia (low oxygen supply) aids...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (17): 3990–3999.
Published: 1 September 2013
... to form tight junctions and express very little endogenous Crumbs3, to show that inducing expression of the polarity protein Scribble is sufficient to promote tight junction formation. We show this occurs through an epithelial-to-mesenchymal (EMT) pathway that involves Scribble suppressing ERK...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (12): 2740–2746.
Published: 15 June 2013
...Wu Zhou; Jean Paul Thiery Summary Epithelial–mesenchymal transition (EMT) can be induced by several pleiotropically activated transcription factors, including the zinc-finger E-box-binding protein Zeb1. Mechanisms regulating Zeb1 expression have been partly uncovered, showing a critical role...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (9): 1981–1991.
Published: 1 May 2013
...-induced epithelial-to-mesenchymal transition (EMT), engage signaling molecules that normally facilitate cellular migration and invasion of mesenchymal cells. We identify lipoma preferred partner (LPP) as an indispensable regulator of TGFβ-induced migration and invasion of ErbB2-expressing breast cancer...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (3): 722–731.
Published: 1 February 2013
... ACAP2 Cadherin Cancer EGF receptor Epithelial–mesenchymal transition EMT Erk Glioma Integrin Tumor invasiveness The migratory potential of cells is determined by the composition of the receptor proteome present at the cell surface. Integrins engage components of the extracellular matrix...
Includes: Supplementary data
Journal Articles