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Keywords: EDEM
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Journal Articles
J Cell Sci (2009) 122 (24): 4465–4472.
Published: 15 December 2009
... ( http://www.sph.uth.tmc.edu/Retnet/ ). GPCR Molecular chaperone Rhodopsin ERAD EDEM Quality control Neurodegeneration Retinitis pigmentosa Traffic © The Company of Biologists Limited 2009 2009 29 9 2009 * Author for correspondence ( michael.cheetham@ucl.ac.uk...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (17): 2814–2823.
Published: 01 September 2008
..., the absence of N-linked oligosaccharides did not seem to affect intracellular localization and processing of ΔF508 CFTR. CFTR Glycosylation Glycoprotein Processing Calnexin EDEM The carbohydrate moieties of glycoproteins often do not play a role in their catalytic activities but contribute...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (21): 4373–4380.
Published: 01 November 2006
... chaperone system is regulated by de-/re-glucosylation cycles catalyzed by GII and UGT1; and how acceleration of N -glycan dismantling upon induction of EDEM variants promotes ER-associated degradation (ERAD) under conditions of ER stress. In particular, characterization of cells lacking certain ER...